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LM-GlycoRepo

Repository for lectin-assisted multimodality data

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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms

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Tools

Glycan Converters

LM-GlycomeAtlas

Search Tools

Cross Search Glycan Search Publication Search Programmatic Access

Guidelines

MIRAGE

coagulation factor V

Summary

Gene Symbol

F5

Organism

Homo sapiens (human)

External Links

NCBI Gene

2153

PubChem

2153

Alliance of Genome Resources

HGNC:3542

Annotation

Keyword

3D-structure
Calcium
Copper
Disease variant
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Repeat
Secreted
Signal
Sulfation
Thrombophilia
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
P12259	Activated protein C cofactor Proaccelerin, labile factor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
blood coagulation	IBA
blood circulation	IBA
response to vitamin K	IEA

GO Hierarchy

biological process

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

blood circulation

coagulation [inference]

blood coagulation

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin K

response to chemical [inference]

response to nutrient [inference]

response to vitamin [inference]

response to vitamin K

response to organic substance [inference]

response to ketone [inference]

response to vitamin K

response to oxygen-containing compound [inference]

response to ketone [inference]

response to vitamin K

biological regulation [inference]

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
extracellular region	NAS	14718574
extracellular region	TAS
extracellular space	IEA
endoplasmic reticulum lumen	TAS
plasma membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular membrane-bounded organelle [inference]

extracellular vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

COPII-coated ER to Golgi transport vesicle

secretory vesicle [inference]

secretory granule [inference]

platelet alpha granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
copper ion binding	IEA
protein binding	IPI	2844223 28514442 33961781 6323392 9556620

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

copper ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Laccase I

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 3** entries
Gene Ontology
copper ion binding
metal ion binding
oxidoreductase activity

Displaying **all 7** entries
InterPro
Cupredoxin
Multicopper oxidase, C-terminal
Multicopper oxidase, copper-binding site
Multicopper oxidase, second cupredoxin domain
Multicopper oxidase-like, N-terminal
Multicopper oxidase
Multicopper oxidases, conserved site

Disease

Disease Ontology

Displaying entries **11 - 17** of 17 in total

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DO ID	Disease Name	Source
DOID:3526	cerebral infarction	Alliance of Genome Resources
DOID:5082	liver cirrhosis	Alliance of Genome Resources
DOID:5844	myocardial infarction	Alliance of Genome Resources
DOID:6432	pulmonary hypertension	Alliance of Genome Resources
DOID:783	end stage renal disease	Alliance of Genome Resources
DOID:9477	pulmonary embolism	Alliance of Genome Resources
DOID:999	hypereosinophilic syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Ficedula albicollis	101818823		FICAL09082
Ictidomys tridecemlineatus	101973974		ICTTR17540
Chinchilla lanigera	102012615		CHILA15359
Macaca fascicularis	102141482		MACFA19725
Capra hircus	102190058		CAPHI06715
Myotis lucifugus	102425587		MYOLU11407
Astyanax mexicanus	103032429		ASTMX21869
Callorhinchus milii	103183966		CALMI03238
Chlorocebus sabaeus	103230620		CHLSB12236
Carlito syrichta	103263684		CARSF20581

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 7, 2025