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MIRAGE
coagulation factor XI
Summary
- Gene Symbol
-
- F11
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood coagulation
- Direct protein sequencing
- Disease variant
- Disulfide bond
- Glycoprotein
- Heparin-binding
- Reference proteome
- Repeat
- Secreted
- Serine protease
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P03951 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood coagulation | ||
| blood coagulation | ||
| plasminogen activation | ||
| positive regulation of fibrinolysis |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space | ||
| plasma membrane | ||
| membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase activity | ||
| protein binding | ||
| heparin binding | ||
| identical protein binding | ||
| serine-type aminopeptidase activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- trypsin
- Functional Category
-
- E: Amino acid transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| hydrolase activity |
| proteolysis |
| serine-type endopeptidase activity |
| serine-type peptidase activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060903 | thrombosis | |
| DOID:2229 | factor XI deficiency |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 2160 | Xenbase:XB-GENE-985051 | ||
| 3818 | Xenbase:XB-GENE-985051 | ||
| 16621 | Xenbase:XB-GENE-985051 | ||
| 109821 | Xenbase:XB-GENE-985051 | MOUSE57653 | |
| 290757 | RATNO10634 | ||
| 407998 | BOVIN21961 | ||
| 461643 | PANTR34936 | ||
| 475623 | CANLF04766 | ||
| 475624 | CANLF04766 | ||
| 702117 | MACMU36677 |
