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catenin alpha 3

Summary

Gene Symbol

Ctnna3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

216033

PubChem

216033

Alliance of Genome Resources

MGI:2661445

Annotation

Keyword

Cell adhesion
Cell junction
Coiled coil
Cytoskeleton
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q65CL1	Alpha T-catenin Cadherin-associated protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cell-cell adhesion	IBA IDA ISO	11590244
regulation of heart rate by cardiac conduction	IEA ISO
cell migration	IBA
regulation of ventricular cardiac muscle cell action potential	IEA ISO
bundle of His cell-Purkinje myocyte adhesion involved in cell communication	IEA ISO

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

homotypic cell-cell adhesion [inference]

cardiac muscle cell-cardiac muscle cell adhesion [inference]

bundle of His cell-Purkinje myocyte adhesion involved in cell communication

heterotypic cell-cell adhesion [inference]

bundle of His cell-Purkinje myocyte adhesion involved in cell communication

cell motility [inference]

cell migration

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of actin filament-based process [inference]

regulation of actin filament-based movement [inference]

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of muscle system process [inference]

regulation of muscle contraction [inference]

regulation of striated muscle contraction [inference]

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of blood circulation [inference]

regulation of heart contraction [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of cardiac muscle contraction [inference]

regulation of cardiac muscle cell contraction [inference]

regulation of ventricular cardiac muscle cell action potential

cardiac conduction [inference]

regulation of heart rate by cardiac conduction

regulation of action potential [inference]

regulation of cardiac muscle cell action potential [inference]

regulation of ventricular cardiac muscle cell action potential

regulation of biological quality [inference]

regulation of heart rate [inference]

regulation of heart rate by cardiac conduction

regulation of membrane potential [inference]

regulation of action potential [inference]

regulation of cardiac muscle cell action potential [inference]

regulation of ventricular cardiac muscle cell action potential

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
desmosome	IEA
adherens junction	IBA IDA	19129494
fascia adherens	IBA IDA ISO ISS	17535849
lamellipodium	IDA	14657280
cytoskeleton	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

anchoring junction [inference]

cell-cell junction [inference]

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11590244 17535849
actin filament binding	IBA IEA
beta-catenin binding	IBA IEA ISO
cadherin binding	TAS	11590244

GO Hierarchy

molecular function

binding [inference]

protein binding

beta-catenin binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

cell adhesion molecule binding [inference]

cadherin binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

catenin alpha-3

Functional Category

J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms
U: Intracellular trafficking, secretion, and vesicular transport

Displaying **all 4** entries
Gene Ontology
actin filament binding
beta-catenin binding
cadherin binding
cell migration

Displaying **all 3** entries
InterPro
Alpha-catenin/vinculin-like superfamily
Alpha-catenin
Vinculin/alpha-catenin

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110084	arrhythmogenic right ventricular dysplasia 13	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	29119		HGNC:2511	HUMAN01320
Drosophila melanogaster	40517		FB:FBgn0010215
Caenorhabditis elegans	179624		WB:WBGene00001978
Rattus norvegicus	361839	10116_1:0051c9	RGD:1562230	RATNO21988
Macaca mulatta	696040			MACMU46564
Pan troglodytes	746091			PANTR00739
Bos taurus	780777			BOVIN22416
Equus caballus	100062915			HORSE17915
Sus scrofa	100153974			PIGXX07685
Taeniopygia guttata	100227386			TAEGU26848

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements