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RAB21, member RAS oncogene family

Summary

Gene Symbol

Rab21

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

216344

PubChem

216344

Alliance of Genome Resources

MGI:894308

Annotation

Keyword

Acetylation
Cell projection
Cytoplasmic vesicle
Direct protein sequencing
Endoplasmic reticulum
Endosome
GTP-binding
Golgi apparatus
Membrane
Methylation
Nucleotide-binding
Prenylation
Protein transport
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P35282	Rab-12
Q0PD35

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
intracellular protein transport	IBA
anterograde axonal transport	ISO
anterograde axonal transport	IEA
protein transport	IEA
regulation of exocytosis	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rab protein signal transduction

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

organic substance transport [inference]

protein transport

intracellular protein transport

nitrogen compound transport [inference]

protein transport

intracellular protein transport

microtubule-based transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

establishment of protein localization [inference]

protein transport

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

cytoskeleton-dependent intracellular transport [inference]

transport along microtubule [inference]

axo-dendritic transport [inference]

axonal transport [inference]

anterograde axonal transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

intracellular protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of exocytosis

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of growth [inference]

regulation of cell growth [inference]

regulation of extent of cell growth [inference]

regulation of axon extension

regulation of developmental growth [inference]

regulation of axon extension

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of dendrite morphogenesis

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of developmental growth [inference]

regulation of axon extension

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rab protein signal transduction

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of cellular process [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of cell morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of dendrite morphogenesis

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular component organization [inference]

regulation of cell growth [inference]

regulation of extent of cell growth [inference]

regulation of axon extension

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of dendrite morphogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendrite development [inference]

regulation of dendrite morphogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of dendrite morphogenesis

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

positive regulation of intracellular transport [inference]

positive regulation of early endosome to late endosome transport

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of vesicle-mediated transport [inference]

regulation of exocytosis

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of receptor-mediated endocytosis [inference]

positive regulation of receptor-mediated endocytosis

regulation of early endosome to late endosome transport [inference]

positive regulation of early endosome to late endosome transport

regulation of secretion by cell [inference]

regulation of exocytosis

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of dendrite morphogenesis

regulation of biological quality [inference]

regulation of protein stability [inference]

protein stabilization

Displaying entries **1 - 5** of 20 in total

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GO Term	Evidence Code	PMID
Golgi membrane	IEA
endosome	ISO
early endosome	IBA
endoplasmic reticulum membrane	IEA
trans-Golgi network	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm [inference]

cytoplasmic region [inference]

plasma membrane bounded cell projection cytoplasm [inference]

neuron projection cytoplasm [inference]

axon cytoplasm

endomembrane system

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

plasma membrane region [inference]

cleavage furrow

cell junction [inference]

synapse

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

cytoplasmic side of endosome membrane [inference]

cytoplasmic side of early endosome membrane

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
GTPase activity	ISS
GTPase activity	ISO
GTPase activity	IBA
protein binding	IPI	16754960 19368996
GTP binding	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ion binding [inference]

anion binding [inference]

GDP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ras-related protein rab-21

Functional Category

E: Amino acid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
GTP binding
Rab protein signal transduction
nucleotide binding

Displaying **all 4** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Rab21
Small GTP-binding protein domain
Small GTPase

Ortholog

Displaying entries **71 - 72** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Jaculus jaculus	123463998		JACJA01137
Ursus americanus	123787122		URSAM04018

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements