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amplified in osteosarcoma

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

216440

PubChem

216440

Alliance of Genome Resources

MGI:1924301

Annotation

Keyword

Alternative splicing
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Lectin
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8K2C7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
ubiquitin-dependent protein catabolic process	ISS
ubiquitin-dependent protein catabolic process	ISO
protein targeting	ISO
protein targeting	IEA
protein retention in ER lumen	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

ERAD pathway

cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to chemical [inference]

response to organic substance [inference]

response to organonitrogen compound [inference]

ERAD pathway

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

ERAD pathway

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

organic substance transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

maintenance of protein localization in organelle [inference]

maintenance of protein localization in endoplasmic reticulum [inference]

protein retention in ER lumen

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

endoplasmic reticulum to cytosol transport [inference]

retrograde protein transport, ER to cytosol

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein targeting

protein transport [inference]

intracellular protein transport [inference]

protein exit from endoplasmic reticulum [inference]

retrograde protein transport, ER to cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular process [inference]

signal transduction [inference]

endoplasmic reticulum unfolded protein response

negative regulation of cellular process [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

negative regulation of intracellular transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

regulation of retrograde protein transport, ER to cytosol [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

negative regulation of protein localization [inference]

negative regulation of establishment of protein localization [inference]

negative regulation of protein transport [inference]

negative regulation of intracellular protein transport [inference]

negative regulation of protein exit from endoplasmic reticulum [inference]

negative regulation of retrograde protein transport, ER to cytosol

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	ISO
endoplasmic reticulum lumen	ISS
endoplasmic reticulum lumen	ISO
endoplasmic reticulum lumen	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protease binding	ISO
protease binding	IEA
protein binding	ISS
protein binding	IPI	10403379
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

protease binding

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protein os-9

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
endoplasmic reticulum unfolded protein response
retrograde protein transport, ER to cytosol

Displaying **all 4** entries
InterPro
MRH domain
Mannose-6-phosphate receptor binding domain superfamily
Protein OS-9-like
Protein OS9-like domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements