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MIRAGE
ADAM metallopeptidase with thrombospondin type 1 motif 2

Summary
Gene Symbol
  • Adamts2
Organism
Mus musculus (house mouse)
NCBI Gene
216725
PubChem
216725
Alliance of Genome Resources
Annotation
Keyword
  • Collagen degradation
  • Direct protein sequencing
  • Disulfide bond
  • Extracellular matrix
  • Glycoprotein
  • Metal-binding
  • Metalloprotease
  • Reference proteome
  • Repeat
  • Signal
  • Zinc
  • Zymogen
Proteins
Displaying 1 entry
UniProt Protein Name
Q8C9W3
  • Procollagen I N-proteinase
  • Procollagen I/II amino propeptide-processing enzyme
  • Procollagen N-endopeptidase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 8 in total
GO Term Evidence Code PMID
proteolysis
spermatogenesis
protein processing
extracellular matrix organization
collagen fibril organization
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
a disintegrin and metalloproteinase
Functional Category
  • T: Signal transduction mechanisms
  • X: Mobilome: prophages, transposons
Displaying all 5 entries
Gene Ontology
extracellular matrix organization
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis
Displaying all 9 entries
InterPro
ADAMTS, cysteine-rich domain 2
ADAMTS/ADAMTS-like, Spacer 1
ADAMTS/ADAMTS-like, cysteine-rich domain 3
ADAMTS/ADAMTS-like
Metallopeptidase, catalytic domain superfamily
PLAC
Peptidase M12B, ADAM/reprolysin
Thrombospondin type-1 (TSP1) repeat superfamily
Thrombospondin type-1 (TSP1) repeat
Ortholog
Displaying entries 1 - 10 of 46 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
9509 Xenbase:XB-GENE-492342 HUMAN82655
216725 Xenbase:XB-GENE-492342
282401 BOVIN32058
287899 RATNO01803
462325 PANTR37001
481453 CANLF01981
100029340 MONDO09178
100224296 TAEGU04132
100395899 CALJA26948
100447800 PONAB29254
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025