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CDC42 binding protein kinase beta

Summary

Gene Symbol

Cdc42bpb

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

217866

PubChem

217866

Alliance of Genome Resources

MGI:2136459

Annotation

Keyword

ATP-binding
Cell junction
Cell membrane
Cell projection
Coiled coil
Cytoplasm
Direct protein sequencing
Magnesium
Methylation
Phosphoprotein
Reference proteome
Serine/threonine-protein kinase
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TT50	CDC42-binding protein kinase beta DMPK-like beta Myotonic dystrophy kinase-related CDC42-binding kinase beta

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
actomyosin structure organization	IBA IEA ISO
actin cytoskeleton organization	ISO ISS
protein phosphorylation	ISO ISS
cell migration	IEA ISO
chromatin remodeling	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

actomyosin structure organization

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cell leading edge	ISS
plasma membrane	IEA
lamellipodium	ISS
actomyosin	IBA IEA ISO
cell-cell junction	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	12522145 25107909
protein serine kinase activity	IEA
protein-containing complex binding	IEA ISO
small GTPase binding	IEA ISO
protein serine/threonine kinase activity	IBA ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

binding [inference]

protein binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

serine/threonine-protein kinase MRCK beta

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actomyosin structure organization
cytoskeleton organization
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity

Displaying 1 entry
InterPro
Protein kinase domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060669	cerebral cavernous malformation	Alliance of Genome Resources
DOID:14227	azoospermia	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of **107** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Macaca nemestrina	105467372		MACNE10644
Cercocebus atys	105596734		CERAT09135
Aotus nancymaae	105730163		AOTNA17037
Propithecus coquereli	105812579		PROCO22557
Microcebus murinus	105861080		MICMU04564
Dipodomys ordii	105983137	10020_0:00025b
Salmo salar	106571112		SALSA42834
Salmo salar	106607646		SALSA128980
Equus asinus asinus	106839626		EQUAS06350
Marmota marmota marmota	107150826	9994_0:000ace

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Annotation

OrthoDB (Group)

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Acknowledgements