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FCH domain only 2

Summary

Gene Symbol

Fcho2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

218503

PubChem

218503

Alliance of Genome Resources

MGI:3505790

Annotation

Keyword

Alternative splicing
Coated pit
Coiled coil
Disulfide bond
Endocytosis
Isopeptide bond
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q3UQN2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
synaptic vesicle endocytosis	IGI	20448150
synaptic vesicle endocytosis	IBA
clathrin-dependent endocytosis	ISS
clathrin-dependent endocytosis	ISO
clathrin-dependent endocytosis	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

membrane organization [inference]

membrane invagination

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis [inference]

clathrin-dependent endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

localization within membrane [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to membrane [inference]

protein localization to plasma membrane

protein localization to cell periphery [inference]

protein localization to plasma membrane

Displaying entry **11 - 11** of 11 in total

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GO Term	Evidence Code	PMID
presynaptic endocytic zone membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

synaptic membrane [inference]

presynaptic endocytic zone membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

presynapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
phosphatidylserine binding	IDA	21762413
protein binding	IPI	20448150 21762413
phosphatidylinositol-4,5-bisphosphate binding	IDA	20448150
phosphatidylinositol binding	IDA	21762413
identical protein binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylserine binding

phosphatidylinositol binding

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

modified amino acid binding [inference]

phosphatidylserine binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

SH3-containing GRB2-like protein 3-interacting protein 1

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
clathrin coat assembly
clathrin-dependent endocytosis

Displaying **all 2** entries
InterPro
Mu homology domain
Muniscin, C-terminal

Ortholog

Displaying entries **31 - 40** of 73 in total

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Species	Gene ID	Orthologous MAtrix
Gorilla gorilla gorilla	101139673	GORGO13284
Tursiops truncatus	101327304	TURTR07460
Mustela putorius furo	101673622	MUSPF08270
Chrysemys picta bellii	101946084	CHRPI03376
Chinchilla lanigera	102009199	CHILA08041
Macaca fascicularis	102140542	MACFA35718
Capra hircus	102174430	CAPHI12957
Latimeria chalumnae	102360754	LATCH11642
Myotis lucifugus	102442913	MYOLU00264
Pelodiscus sinensis	102463894	PELSI17646