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Repository for lectin-assisted multimodality data

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Guidelines

MIRAGE

interleukin 31 receptor A

Summary

Gene Symbol

Il31ra

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

218624

PubChem

218624

Alliance of Genome Resources

MGI:2180511

Annotation

Keyword

Alternative splicing
Cell membrane
Cell projection
Glycoprotein
Immunity
Receptor
Reference proteome
Repeat
Signal
Synapse
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8K5B1	GLM-R Gp130-like monocyte receptor Novel cytokine receptor 10 ZcytoR17
A0A286YDE2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

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GO Term	Evidence Code	PMID
glandular epithelial cell differentiation	IMP	19414760
acute inflammatory response to antigenic stimulus	IMP	19414760
receptor signaling pathway via JAK-STAT	ISS
positive regulation of cell population proliferation	ISS
positive regulation of cell population proliferation	ISO

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

production of molecular mediator of immune response [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

glandular epithelial cell differentiation

multicellular organismal process [inference]

cytokine production [inference]

cytokine production involved in immune response [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

mononuclear cell differentiation [inference]

monocyte differentiation

myeloid cell differentiation [inference]

myeloid leukocyte differentiation [inference]

monocyte differentiation

epithelial cell differentiation [inference]

columnar/cuboidal epithelial cell differentiation [inference]

glandular epithelial cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response [inference]

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus

acute inflammatory response [inference]

acute inflammatory response to antigenic stimulus

defense response to other organism

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity [inference]

T cell cytokine production [inference]

CD4-positive, alpha-beta T cell cytokine production [inference]

T-helper 2 cell cytokine production

inflammatory response to antigenic stimulus [inference]

acute inflammatory response to antigenic stimulus

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

receptor signaling pathway via STAT [inference]

receptor signaling pathway via JAK-STAT

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of peptidyl-tyrosine phosphorylation [inference]

regulation of tyrosine phosphorylation of STAT protein [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of tyrosine phosphorylation of STAT protein

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
external side of plasma membrane	IDA	21182835
external side of plasma membrane	IBA
membrane	ISO	11877449
axon	IEA
presynaptic membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine receptor activity	ISO	11877449
cytokine receptor activity	IBA
cytokine binding	IBA
cytokine binding	IPI	21182835

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytokine binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

cytokine receptor activity

immune receptor activity [inference]

cytokine receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Interleukin-31 receptor subunit alpha

Functional Category

I: Lipid transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025