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Guidelines

MIRAGE

tenascin R

Summary

Gene Symbol

Tnr

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

21960

PubChem

21960

Alliance of Genome Resources

MGI:99516

Annotation

Keyword

Alternative splicing
Cell adhesion
Coiled coil
Disulfide bond
EGF-like domain
Extracellular matrix
Phosphoprotein
Proteoglycan
Reference proteome
Repeat
Sialic acid
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8BYI9	Janusin Neural recognition molecule J1-160/180 Restrictin

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **26 - 27** of 27 in total

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GO Term	Evidence Code	PMID
long-term synaptic potentiation	IMP	11161481 17537973
neuroblast migration	IMP	15034584

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

cell adhesion [inference]

cell-cell adhesion [inference]

neuron cell-cell adhesion

cell growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension involved in regeneration

cell motility [inference]

cell migration [inference]

forebrain cell migration [inference]

telencephalon cell migration

neuroblast migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

extracellular structure organization [inference]

extracellular matrix organization

external encapsulating structure organization [inference]

extracellular matrix organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning

neuromuscular process [inference]

neuromuscular process controlling balance

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning

locomotory behavior [inference]

locomotory exploration behavior

exploration behavior [inference]

locomotory exploration behavior

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension involved in regeneration

developmental growth [inference]

developmental cell growth [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension involved in regeneration

developmental growth involved in morphogenesis [inference]

sprouting of injured axon [inference]

axon extension involved in regeneration

neuron projection extension [inference]

axon extension involved in regeneration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

negative regulation of synaptic transmission

positive regulation of synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission [inference]

synaptic transmission, glutamatergic

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

regulation of locomotion [inference]

regulation of cell motility [inference]

regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of synaptic transmission [inference]

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of synaptic transmission

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of response to wounding [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of response to wounding [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of developmental growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of developmental growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cellular process [inference]

regulation of cell communication [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

regulation of transmission of nerve impulse [inference]

positive regulation of transmission of nerve impulse

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

negative regulation of synaptic transmission

positive regulation of synaptic transmission [inference]

regulation of synaptic transmission, glutamatergic [inference]

positive regulation of synaptic transmission, glutamatergic

regulation of cell adhesion

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion

regulation of cell differentiation

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of synaptic transmission [inference]

positive regulation of transmission of nerve impulse

negative regulation of cellular process [inference]

negative regulation of cell adhesion

negative regulation of cell-cell adhesion

negative regulation of cell communication [inference]

negative regulation of synaptic transmission

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of extent of cell growth [inference]

regulation of axon extension [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

regulation of sprouting of injured axon [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axon extension involved in regeneration [inference]

negative regulation of axon extension involved in regeneration

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of axonogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cellular response to stress [inference]

regulation of neuron projection regeneration [inference]

regulation of axon regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

negative regulation of neuron projection regeneration [inference]

negative regulation of axon regeneration [inference]

negative regulation of sprouting of injured axon [inference]

negative regulation of axon extension involved in regeneration

regulation of cell motility [inference]

regulation of cell migration

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

regulation of transmission of nerve impulse [inference]

positive regulation of transmission of nerve impulse

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system process [inference]

positive regulation of transmission of nerve impulse

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of axon extension

negative regulation of axon extension involved in regeneration

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

long-term synaptic potentiation

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA
cell surface	IDA	12056833
extracellular matrix	IDA	19141078 7530142
membrane raft	IDA	12056833

GO Hierarchy

cellular component

protein-containing complex [inference]

protein complex involved in cell adhesion [inference]

protein complex involved in cell-matrix adhesion [inference]

tenascin complex

cellular anatomical entity [inference]

membrane [inference]

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

extracellular matrix of synaptic cleft

perisynaptic extracellular matrix

perineuronal net

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	ISO
sphingolipid binding	TAS	12056833

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

sphingolipid binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Tenascin

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 2** entries
Gene Ontology
neuron projection development
regulation of cell adhesion

Displaying **all 8** entries
InterPro
EGF-like domain
Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Fibrinogen-like, C-terminal
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
Tenascin, EGF-like domain

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025