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protein-tyrosine sulfotransferase 2

Summary

Gene Symbol

Tpst2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22022

PubChem

22022

Alliance of Genome Resources

MGI:1309516

Annotation

Keyword

Disulfide bond
Glycoprotein
Golgi apparatus
Proteomics identification
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TQN1
O88856	Tyrosylprotein sulfotransferase 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
peptidyl-tyrosine sulfation	IDA IMP ISO ISS	17046811 9733778
fusion of sperm to egg plasma membrane involved in single fertilization	IMP	21339297
prevention of polyspermy	IMP	21339297

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

sulfation [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

macromolecule modification [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

cellular process [inference]

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

sulfation [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

membrane fusion [inference]

plasma membrane fusion [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

reproductive process [inference]

cellular process involved in reproduction in multicellular organism [inference]

fusion of sperm to egg plasma membrane involved in single fertilization

prevention of polyspermy

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

regulation of reproductive process [inference]

regulation of fertilization [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

negative regulation of reproductive process [inference]

negative regulation of fertilization [inference]

prevention of polyspermy

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi lumen	IDA	20011239 3121635
Golgi apparatus	IBA
trans-Golgi network	IDA ISO	16859706 3121635
Golgi membrane	IEA
endoplasmic reticulum	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

Golgi lumen

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein-tyrosine sulfotransferase activity	IBA IDA IMP ISO ISS	17046811 9733778
protein homodimerization activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity [inference]

protein-tyrosine sulfotransferase activity

catalytic activity, acting on a protein [inference]

protein-tyrosine sulfotransferase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

protein-tyrosine sulfotransferase 2

Functional Category

J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
protein-tyrosine sulfotransferase activity
transferase activity

Displaying **all 2** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Protein-tyrosine sulfotransferase-like

Ortholog

Displaying entries **1 - 10** of 91 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8459		HGNC:12021	HUMAN59717
Drosophila melanogaster	32312		FB:FBgn0086674
Caenorhabditis elegans	176684		WB:WBGene00013737
Rattus norvegicus	288719	10116_1:003e26	RGD:1305331	RATNO05987
Danio rerio	393391		ZFIN:ZDB-GENE-040426-1400
Pan troglodytes	458726			PANTR26235
Canis lupus familiaris	486332			CANLF10436
Bos taurus	540183			BOVIN09747
Xenopus tropicalis	549785		Xenbase:XB-GENE-962493
Macaca mulatta	715338			MACMU00937