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jumonji domain containing 1C

Summary

Gene Symbol

JMJD1C

Organism

Homo sapiens (human)

External Links

NCBI Gene

221037

PubChem

221037

Alliance of Genome Resources

HGNC:12313

Annotation

Keyword

3D-structure
Alternative splicing
Chromatin regulator
Dioxygenase
Iron
Isopeptide bond
Metal-binding
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q15652	Jumonji domain-containing protein 1C Thyroid receptor-interacting protein 8
B7ZLC8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
chromatin remodeling	IEA
regulation of transcription, DNA-templated	TAS	7776974
regulation of DNA-templated transcription	TAS	7776974
regulation of transcription by RNA polymerase II	IBA
blood coagulation	TAS

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

multicellular organismal process [inference]

coagulation [inference]

blood coagulation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

regulation of transcription by RNA polymerase II

regulation of biological quality [inference]

regulation of body fluid levels [inference]

hemostasis [inference]

blood coagulation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
histone deacetylase complex	IBA
chromatin	IBA
nucleoplasm	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

nuclear protein-containing complex [inference]

histone deacetylase complex

catalytic complex [inference]

histone deacetylase complex

cellular anatomical entity [inference]

nucleoplasm

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
transcription coregulator activity	IBA
protein binding	IPI	17353003 33640491
zinc ion binding	IEA
chromatin DNA binding	IBA
histone H3K9 demethylase activity	TAS

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

dioxygenase activity

demethylase activity [inference]

protein demethylase activity [inference]

histone demethylase activity [inference]

histone H3 demethylase activity [inference]

histone H3K9 demethylase activity

catalytic activity, acting on a protein [inference]

protein demethylase activity [inference]

histone demethylase activity [inference]

histone H3 demethylase activity [inference]

histone H3K9 demethylase activity

histone modifying activity [inference]

histone demethylase activity [inference]

histone H3 demethylase activity [inference]

histone H3K9 demethylase activity

binding [inference]

protein binding

transcription factor binding [inference]

DNA-binding transcription factor binding [inference]

RNA polymerase II-specific DNA-binding transcription factor binding [inference]

nuclear receptor binding [inference]

nuclear thyroid hormone receptor binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

chromatin binding [inference]

chromatin DNA binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

chromatin DNA binding

transcription regulator activity [inference]

transcription coregulator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

lysine-specific demethylase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
chromatin DNA binding
histone H3K9 demethylase activity

Displaying **all 2** entries
InterPro
Histone demethylase JHDM2-like
JmjC domain

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	51780	FB:FBgn0037703
Drosophila melanogaster	55818	FB:FBgn0037703
Drosophila melanogaster	104263	FB:FBgn0037703
Mus musculus	108829	Xenbase:XB-GENE-1008867	MOUSE00389
Rattus norvegicus	171120		RATNO22162
Xenopus tropicalis	221037	Xenbase:XB-GENE-1008867
Drosophila melanogaster	277250	FB:FBgn0037703
Pan troglodytes	450489		PANTR00728
Canis lupus familiaris	479221		CANLF14596
Danio rerio	558436		DANRE03610