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transthyretin

Summary

Gene Symbol

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22139

PubChem

22139

Alliance of Genome Resources

MGI:98865

Annotation

Keyword

3D-structure
Gamma-carboxyglutamic acid
Glycoprotein
Phosphoprotein
Reference proteome
Secreted
Signal
Sulfation
Thyroid hormone
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P07309	Prealbumin
Q5M9K1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
retinoid metabolic process	IMP	11036082
negative regulation of glomerular filtration	IMP	11036082
purine nucleobase metabolic process	IBA
phototransduction, visible light	IMP	12484775

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

organonitrogen compound metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular process [inference]

signal transduction [inference]

phototransduction [inference]

phototransduction, visible light

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

cellular lipid metabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

purine nucleobase metabolic process

purine-containing compound metabolic process [inference]

purine nucleobase metabolic process

multicellular organismal process [inference]

system process [inference]

renal system process [inference]

renal system process involved in regulation of systemic arterial blood pressure [inference]

renal system process involved in regulation of blood volume [inference]

regulation of glomerular filtration [inference]

negative regulation of glomerular filtration

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction [inference]

phototransduction, visible light

detection of visible light [inference]

phototransduction, visible light

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of glomerular filtration

regulation of cellular process [inference]

signal transduction [inference]

phototransduction [inference]

phototransduction, visible light

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of renal system process [inference]

regulation of glomerular filtration [inference]

negative regulation of glomerular filtration

negative regulation of multicellular organismal process [inference]

negative regulation of glomerular filtration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular region	IDA	11036082
extracellular space	ISO
extracellular space	IBA
protein-containing complex	ISO

GO Hierarchy

cellular component

protein-containing complex

cellular anatomical entity [inference]

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
hormone activity	IEA
protein binding	IPI	23105095
hormone binding	ISO
identical protein binding	ISO
identical protein binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity [inference]

hormone activity

identical protein binding

hormone binding

thyroid hormone binding

protein-containing complex binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

hormone activity

molecular sequestering activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Transthyretin

Functional Category

F: Nucleotide transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
hormone activity
purine nucleobase metabolic process
thyroid hormone binding

Displaying **all 5** entries
InterPro
Transthyretin, conserved site
Transthyretin, thyroxine binding site
Transthyretin/hydroxyisourate hydrolase domain superfamily
Transthyretin/hydroxyisourate hydrolase domain
Transthyretin/hydroxyisourate hydrolase