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tubulin, alpha 1B

Summary

Gene Symbol

Tuba1b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22143

PubChem

22143

Alliance of Genome Resources

MGI:107804

Annotation

Keyword

Acetylation
Cytoskeleton
Direct protein sequencing
GTP-binding
Hydrolase
Isopeptide bond
Magnesium
Metal-binding
Methylation
Microtubule
Nitration
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P05213	Alpha-tubulin 2 Alpha-tubulin isotype M-alpha-2 Tubulin alpha-2 chain

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	ISO
microtubule cytoskeleton organization	IBA
microtubule cytoskeleton organization	IEA
mitotic cell cycle	IBA
cellular response to interleukin-4	IDA	9798653

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

cell cycle [inference]

mitotic cell cycle

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interleukin-4 [inference]

cellular response to interleukin-4

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-4

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
cytosol	TAS
microtubule	ISO
microtubule	IBA
cytoplasmic microtubule	IDA	19103752

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

membrane microdomain [inference]

membrane raft

cell projection [inference]

plasma membrane bounded cell projection [inference]

cilium

myelin sheath

organelle [inference]

membrane-bounded organelle [inference]

cilium

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

microtubule cytoskeleton

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

cytoplasmic microtubule

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
double-stranded RNA binding	ISO	21266579
GTPase activity	ISS
GTPase activity	ISO
structural constituent of cytoskeleton	ISO
structural constituent of cytoskeleton	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

structural molecule activity [inference]

structural constituent of cytoskeleton

binding [inference]

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

double-stranded RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

tubulin alpha chain

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis

Displaying **all 7** entries
Gene Ontology
GTP binding
cytoskeleton organization
hydrolase activity
microtubule cytoskeleton organization
microtubule-based process
nucleotide binding
structural constituent of cytoskeleton

Displaying **all 9** entries
InterPro
Alpha tubulin
Tubulin, C-terminal
Tubulin, conserved site
Tubulin/FtsZ, 2-layer sandwich domain
Tubulin/FtsZ, C-terminal
Tubulin/FtsZ, GTPase domain superfamily
Tubulin/FtsZ, GTPase domain
Tubulin/FtsZ-like, C-terminal domain
Tubulin

Ortholog

Displaying entries **1 - 10** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	7277	SGD:S000004593
Homo sapiens	7846	Xenbase:XB-GENE-22063827	HUMAN12441
Homo sapiens	10376	Xenbase:XB-GENE-490055	HUMAN12435
Xenopus tropicalis	22142	Xenbase:XB-GENE-22063827
Xenopus tropicalis	22143	Xenbase:XB-GENE-490055
Saccharomyces cerevisiae S288C	22144	SGD:S000004593
Saccharomyces cerevisiae S288C	22145	SGD:S000004593
Danio rerio	22146	ZFIN:ZDB-GENE-061114-1
Saccharomyces cerevisiae S288C	22147	SGD:S000004593
Saccharomyces cerevisiae S288C	53857	SGD:S000004593

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements