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MIRAGE
lysine (K)-specific demethylase 6A
Summary
- Gene Symbol
-
- Kdm6a
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- Alternative splicing
- Chromatin regulator
- Dioxygenase
- Iron
- Metal-binding
- Methylation
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Repeat
- TPR repeat
- Zinc
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| in utero embryonic development | ||
| neural tube closure | ||
| heart morphogenesis | ||
| respiratory system process | ||
| chromatin remodeling |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of programmed cell death [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nucleus | ||
| nucleoplasm | ||
| histone methyltransferase complex | ||
| histone methyltransferase complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| RNA polymerase II cis-regulatory region sequence-specific DNA binding | ||
| protein binding | ||
| chromatin DNA binding | ||
| chromatin DNA binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- lysine-specific demethylase
- Functional Category
-
- E: Amino acid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| chromatin DNA binding |
| histone H3K27me2/H3K27me3 demethylase activity |
| histone demethylase activity |
| metal ion binding |
| oxidoreductase activity |
| regulation of gene expression |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080188 | chronic myelomonocytic leukemia |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7403 | Xenbase:XB-GENE-960316 | HUMAN100342 | |
| 7404 | Xenbase:XB-GENE-960316 | ||
| 22289 | Xenbase:XB-GENE-960316 | ||
| 23135 | SGD:S000000316 | ||
| 216850 | SGD:S000000316 | ||
| 280952 | BOVIN37190 | ||
| 465593 | PANTR45839 | ||
| 491845 | CANLF19711 | ||
| 569207 | DANRE38740 | ||
| 569277 | DANRE44687 |
