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voltage-dependent anion channel 3

Summary

Gene Symbol

Vdac3

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22335

PubChem

22335

Alliance of Genome Resources

MGI:106922

Annotation

Keyword

Acetylation
Direct protein sequencing
Isopeptide bond
Mitochondrion outer membrane
NAD
Nucleotide-binding
Phosphoprotein
Porin
Reference proteome
Spermatogenesis
Transmembrane beta strand
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q60931	Outer mitochondrial membrane protein porin 3
Q3TX38
Q5EBQ0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
behavioral fear response	IMP	11907043
chemical synaptic transmission	IMP	11907043
neuron-neuron synaptic transmission	IMP	11907043
spermatogenesis	IMP	35228556
learning	IMP	11907043

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

neuron-neuron synaptic transmission

cellular process involved in reproduction in multicellular organism [inference]

sperm mitochondrial sheath assembly

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

sperm mitochondrial sheath assembly

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

cellular process involved in reproduction in multicellular organism [inference]

sperm mitochondrial sheath assembly

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning

behavior [inference]

behavioral defense response [inference]

behavioral fear response

learning or memory [inference]

learning

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

response to stimulus [inference]

response to stress [inference]

defense response [inference]

behavioral defense response [inference]

behavioral fear response

multicellular organismal response to stress [inference]

fear response [inference]

behavioral fear response

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

synaptic signaling [inference]

trans-synaptic signaling [inference]

anterograde trans-synaptic signaling [inference]

chemical synaptic transmission

neuron-neuron synaptic transmission

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IDA	23028046
mitochondrion	HDA	14651853 18614015
mitochondrial outer membrane	IBA
mitochondrial outer membrane	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

pore complex

cellular anatomical entity [inference]

membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleotide binding	IEA
protein binding	IPI	33536340 35228556
voltage-gated monoatomic anion channel activity	IBA
voltage-gated monoatomic anion channel activity	IEA
porin activity	IEA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

wide pore channel activity [inference]

porin activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Voltage-dependent anion-selective channel

Functional Category

O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
porin activity

Displaying **all 3** entries
InterPro
Eukaryotic porin/Tom40
Porin domain superfamily
Porin, eukaryotic type

Ortholog

Displaying entries **1 - 10** of 97 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	7416	SGD:S000005000
Saccharomyces cerevisiae S288C	7417	SGD:S000005000
Homo sapiens	7419	Xenbase:XB-GENE-949888	HUMAN93675
Saccharomyces cerevisiae S288C	22333	SGD:S000005000
Saccharomyces cerevisiae S288C	22334	SGD:S000005000
Xenopus tropicalis	22335	Xenbase:XB-GENE-949888
Saccharomyces cerevisiae S288C	83529	SGD:S000005000
Saccharomyces cerevisiae S288C	83531	SGD:S000005000
Rattus norvegicus	83532		RATNO10678
Bos taurus	282716		BOVIN22168

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Annotation

OrthoDB (Group)

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Acknowledgements