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MIRAGE

vascular endothelial growth factor C

Summary

Gene Symbol

Vegfc

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22341

PubChem

22341

Alliance of Genome Resources

MGI:109124

Annotation

Keyword

Alternative splicing
Angiogenesis
Cleavage on pair of basic residues
Developmental protein
Differentiation
Direct protein sequencing
Disulfide bond
Glycoprotein
Growth factor
Mitogen
Reference proteome
Repeat
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P97953	Flt4 ligand Vascular endothelial growth factor-related protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 49 in total

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GO Term	Evidence Code	PMID
angiogenesis	ISO
angiogenesis	IEA
response to hypoxia	IBA
positive regulation of cell-matrix adhesion
sprouting angiogenesis	IBA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

cell population proliferation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium

anatomical structure formation involved in morphogenesis [inference]

sprouting angiogenesis

locomotion [inference]

taxis [inference]

chemotaxis [inference]

positive chemotaxis

response to stimulus [inference]

response to stress [inference]

response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia

response to chemical [inference]

response to xenobiotic stimulus

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of mast cell chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein autophosphorylation [inference]

positive regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein autophosphorylation [inference]

positive regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein autophosphorylation [inference]

positive regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein autophosphorylation [inference]

positive regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of vascular endothelial growth factor receptor signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of mast cell chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of positive chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of mast cell chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein modification process [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of locomotion [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of stem cell proliferation [inference]

positive regulation of mesenchymal stem cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell division

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of transport [inference]

positive regulation of secretion [inference]

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of lymphangiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of vascular endothelial growth factor receptor signaling pathway

regulation of response to external stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of chemotaxis [inference]

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of mast cell chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of positive chemotaxis [inference]

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

positive regulation of response to stimulus [inference]

positive regulation of response to external stimulus [inference]

positive regulation of chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of positive chemotaxis [inference]

induction of positive chemotaxis

regulation of cellular response to growth factor stimulus [inference]

regulation of vascular endothelial growth factor receptor signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

regulation of lymphangiogenesis [inference]

positive regulation of lymphangiogenesis

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of lymphangiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of vascular endothelial growth factor receptor signaling pathway

regulation of cell adhesion [inference]

regulation of cell-substrate adhesion [inference]

regulation of cell-matrix adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of phosphate metabolic process [inference]

regulation of phosphorylation [inference]

regulation of protein phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

regulation of protein autophosphorylation [inference]

positive regulation of protein autophosphorylation

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

regulation of peptidyl-tyrosine phosphorylation [inference]

positive regulation of peptidyl-tyrosine phosphorylation

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of stem cell proliferation [inference]

positive regulation of mesenchymal stem cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of glial cell proliferation [inference]

positive regulation of glial cell proliferation

regulation of stem cell proliferation [inference]

regulation of mesenchymal stem cell proliferation [inference]

positive regulation of mesenchymal stem cell proliferation

positive regulation of stem cell proliferation [inference]

positive regulation of mesenchymal stem cell proliferation

regulation of neural precursor cell proliferation [inference]

regulation of neuroblast proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of neural precursor cell proliferation [inference]

positive regulation of neuroblast proliferation

positive regulation of stem cell proliferation [inference]

positive regulation of mesenchymal stem cell proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phosphorylation [inference]

positive regulation of protein phosphorylation [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of cell adhesion [inference]

positive regulation of cell-substrate adhesion [inference]

positive regulation of cell-matrix adhesion

positive regulation of cell division

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cell division [inference]

positive regulation of cell division

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

positive regulation of protein localization [inference]

positive regulation of establishment of protein localization [inference]

positive regulation of protein transport [inference]

positive regulation of protein secretion

regulation of secretion by cell [inference]

regulation of protein secretion [inference]

positive regulation of protein secretion

positive regulation of secretion by cell [inference]

positive regulation of protein secretion

regulation of cell motility [inference]

regulation of cell migration [inference]

regulation of leukocyte migration [inference]

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of leukocyte chemotaxis [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of mast cell chemotaxis [inference]

positive regulation of mast cell chemotaxis

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of leukocyte migration [inference]

positive regulation of leukocyte chemotaxis [inference]

positive regulation of mast cell chemotaxis

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of multicellular organismal process [inference]

regulation of epithelial cell migration [inference]

regulation of endothelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

regulation of blood vessel endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of epithelial cell migration [inference]

positive regulation of endothelial cell migration [inference]

positive regulation of blood vessel endothelial cell migration

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

regulation of gliogenesis [inference]

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of neuroblast proliferation

positive regulation of gliogenesis [inference]

positive regulation of glial cell proliferation

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

positive regulation of angiogenesis

positive regulation of vasculature development [inference]

positive regulation of angiogenesis

regulation of biological quality [inference]

regulation of blood pressure [inference]

negative regulation of blood pressure

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of transferase activity [inference]

regulation of kinase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

regulation of protein kinase activity [inference]

positive regulation of protein kinase activity

positive regulation of transferase activity [inference]

positive regulation of kinase activity [inference]

positive regulation of protein kinase activity

Displaying **all 4** entries
GO Term	Evidence Code	PMID
extracellular space	IDA	24552833 9247316
extracellular space	IBA
extracellular space	HDA	24006456
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

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GO Term	Evidence Code	PMID
protein binding	IPI	25752543
growth factor activity	IBA
growth factor activity	IEA
chemoattractant activity	ISO
chemoattractant activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

vascular endothelial growth factor receptor binding [inference]

vascular endothelial growth factor receptor 3 binding

receptor ligand activity [inference]

growth factor receptor binding [inference]

vascular endothelial growth factor receptor binding [inference]

vascular endothelial growth factor receptor 3 binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vascular endothelial growth factor

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

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Gene Ontology
chemoattractant activity
growth factor activity
induction of positive chemotaxis
positive regulation of angiogenesis
positive regulation of endothelial cell proliferation
positive regulation of mast cell chemotaxis
positive regulation of protein phosphorylation
response to hypoxia
sprouting angiogenesis
vascular endothelial growth factor receptor 3 binding

Displaying **all 4** entries
InterPro
CXCXC repeat
Cystine-knot cytokine
PDGF/VEGF domain
Platelet-derived growth factor, conserved site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050580	hereditary lymphedema	Alliance of Genome Resources

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7424	Xenbase:XB-GENE-484533	HUMAN78220
Xenopus tropicalis	22341	Xenbase:XB-GENE-484533
Rattus norvegicus	114111	Xenbase:XB-GENE-484533	RATNO11878
Bos taurus	282122		BOVIN21887
Danio rerio	403049		DANRE17142
Pan troglodytes	471358		PANTR34858
Monodelphis domestica	100013301		MONDO26340
Equus caballus	100060890		HORSE25060
Ornithorhynchus anatinus	100084886		ORNAN04320
Taeniopygia guttata	100221203		TAEGU24106

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025