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solute carrier family 32 (GABA vesicular transporter), member 1

Summary

Gene Symbol

Slc32a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22348

PubChem

22348

Alliance of Genome Resources

MGI:1194488

Annotation

Keyword

Alternative splicing
Cell projection
Cytoplasmic vesicle
Neurotransmitter transport
Nitration
Reference proteome
Synapse
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
O35633	Solute carrier family 32 member 1 Vesicular GABA and glycine transporter Vesicular GABA transporter
Q49S98	Solute carrier family 32 member 1 Vesicular GABA transporter

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
beta-alanine transport	ISS
beta-alanine transport	ISO
gamma-aminobutyric acid transport	ISO
gamma-aminobutyric acid transport	IBA
glycine transport	ISO

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

developmental process [inference]

anatomical structure development [inference]

hippocampus development

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

neurotransmitter transport [inference]

neurotransmitter loading into synaptic vesicle

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

proton transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

proton transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

gamma-aminobutyric acid import

neutral amino acid transport [inference]

L-amino acid transport [inference]

glycine transport

gamma-aminobutyric acid transport

gamma-aminobutyric acid import

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

gamma-aminobutyric acid import

neutral amino acid transport [inference]

L-amino acid transport [inference]

glycine transport

gamma-aminobutyric acid transport

gamma-aminobutyric acid import

nitrogen compound transport [inference]

amino acid transport [inference]

acidic amino acid transport [inference]

gamma-aminobutyric acid import

neutral amino acid transport [inference]

L-amino acid transport [inference]

glycine transport

gamma-aminobutyric acid transport

gamma-aminobutyric acid import

establishment of localization in cell [inference]

neurotransmitter loading into synaptic vesicle

Displaying entries **1 - 5** of 24 in total

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GO Term	Evidence Code	PMID
plasma membrane	IC	9395291
synaptic vesicle	ISS
synaptic vesicle	ISO	21378974
cell surface	IDA	29107521
dendrite	ISO	12115694

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

bounding membrane of organelle [inference]

transport vesicle membrane [inference]

exocytic vesicle membrane [inference]

synaptic vesicle membrane

cell junction [inference]

synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

dendrite terminus

neuron projection terminus

axon terminus [inference]

cone cell pedicle

presynaptic active zone

cell pole [inference]

cell tip

presynapse

axon terminus [inference]

cone cell pedicle

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GO Term	Evidence Code	PMID
gamma-aminobutyric acid transmembrane transporter activity	ISO
glycine transmembrane transporter activity	ISO
glycine transmembrane transporter activity	IDA	9395291
glycine transmembrane transporter activity	IBA
glycine:proton antiporter activity	IDA	16701208 26912364

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity

gamma-aminobutyric acid:proton antiporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton antiporter activity

amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

glycine transmembrane transporter activity

glycine:proton antiporter activity

L-amino acid transmembrane transporter activity [inference]

glycine transmembrane transporter activity

glycine:proton antiporter activity

gamma-aminobutyric acid transmembrane transporter activity

gamma-aminobutyric acid:proton antiporter activity

amino acid:monoatomic cation antiporter activity [inference]

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

gamma-aminobutyric acid transmembrane transporter activity

gamma-aminobutyric acid:proton antiporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton antiporter activity

amino acid transmembrane transporter activity [inference]

neutral L-amino acid transmembrane transporter activity [inference]

glycine transmembrane transporter activity

glycine:proton antiporter activity

L-amino acid transmembrane transporter activity [inference]

glycine transmembrane transporter activity

glycine:proton antiporter activity

gamma-aminobutyric acid transmembrane transporter activity

gamma-aminobutyric acid:proton antiporter activity

amino acid:monoatomic cation antiporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

amino acid:monoatomic cation antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

amino acid:monoatomic cation antiporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

amino acid:monoatomic cation antiporter activity [inference]

secondary active monocarboxylate transmembrane transporter activity [inference]

gamma-aminobutyric acid:proton antiporter activity

active monoatomic ion transmembrane transporter activity [inference]

amino acid:monoatomic cation antiporter activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Vesicular inhibitory amino acid transporter

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
L-amino acid transmembrane transporter activity

Displaying 1 entry
InterPro
Amino acid transporter, transmembrane domain

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3328	temporal lobe epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 89 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	22348	Xenbase:XB-GENE-489830
Rattus norvegicus	83612		RATNO28995
Homo sapiens	140679	Xenbase:XB-GENE-489830	HUMAN56976
Xenopus tropicalis	176431	Xenbase:XB-GENE-489830
Ciona intestinalis	445774		CIOIN05308
Pan troglodytes	469940		PANTR24850
Canis lupus familiaris	485870		CANLF09533
Macaca mulatta	698315		MACMU01889
Danio rerio	798575		DANRE39378
Monodelphis domestica	100029278		MONDO08640