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adhesion G protein-coupled receptor F5

Summary

Gene Symbol

Adgrf5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

224792

PubChem

224792

Alliance of Genome Resources

MGI:2182928

Annotation

Keyword

Autocatalytic cleavage
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
G5E8Q8	G-protein coupled receptor 116

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
glomerular filtration	IGI	28806758
energy reserve metabolic process	IMP	22971422
energy reserve metabolic process	IBA
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	IEA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

myeloid leukocyte activation [inference]

macrophage activation

system process [inference]

renal system process [inference]

renal filtration [inference]

glomerular filtration

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

developmental process [inference]

anatomical structure morphogenesis [inference]

tube morphogenesis [inference]

blood vessel morphogenesis [inference]

artery morphogenesis [inference]

pharyngeal arch artery morphogenesis

anatomical structure development [inference]

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

cellular developmental process [inference]

cell differentiation [inference]

fat cell differentiation

cell development [inference]

hemopoiesis [inference]

myeloid cell development [inference]

erythrocyte development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

multicellular organismal-level chemical homeostasis [inference]

surfactant homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of primary metabolic process [inference]

regulation of lipid metabolic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of lipid biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of lipid metabolic process [inference]

positive regulation of lipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphorus metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phosphate metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

regulation of phospholipid metabolic process [inference]

regulation of phospholipid biosynthetic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of phosphorus metabolic process [inference]

positive regulation of phosphate metabolic process [inference]

positive regulation of phospholipid metabolic process [inference]

positive regulation of phospholipid biosynthetic process

negative regulation of cellular process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of multicellular organismal process [inference]

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

regulation of macrophage activation [inference]

negative regulation of macrophage activation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

negative regulation of multicellular organismal process [inference]

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of macrophage activation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
cell surface	ISO
cytoplasmic vesicle	ISO
cytoplasmic vesicle	IBA
apical part of cell	IDA	23590306

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

apical part of cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
molecular_function	ND
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Adhesion G protein-coupled receptor F5

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cell surface receptor signaling pathway
energy reserve metabolic process
fat cell differentiation
regulation of lipid metabolic process

Displaying **all 5** entries
InterPro
GAIN domain superfamily
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM
GPS motif
Immunoglobulin-like domain

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	77596	ZFIN:ZDB-GENE-121214-165
Homo sapiens	221395	Xenbase:XB-GENE-6468452	HUMAN85106
Xenopus tropicalis	224792	Xenbase:XB-GENE-6468452
Rattus norvegicus	245977	Xenbase:XB-GENE-6468452	RATNO42593
Danio rerio	266977	ZFIN:ZDB-GENE-121214-165
Canis lupus familiaris	474926		CANLF02819
Bos taurus	532674		BOVIN18611
Macaca mulatta	704887		MACMU33832
Pan troglodytes	739480		PANTR38319
Monodelphis domestica	100014662		MONDO14825

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OrthoDB (Group)

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Acknowledgements