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internexin neuronal intermediate filament protein, alpha

Summary

Gene Symbol

Ina

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

226180

PubChem

226180

Alliance of Genome Resources

MGI:96568

Annotation

Keyword

Acetylation
Coiled coil
Developmental protein
Differentiation
Direct protein sequencing
Glycoprotein
Intermediate filament
Neurogenesis
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P46660	66 kDa neurofilament protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nervous system development	IEA
cell differentiation	IEA
intermediate filament cytoskeleton organization	IMP	14561875
intermediate filament organization	IBA
neurofilament cytoskeleton organization	IGI	10350642

GO Hierarchy

biological process

cellular process [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization

cellular developmental process [inference]

cell differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization

postsynaptic cytoskeleton organization [inference]

postsynaptic intermediate filament cytoskeleton organization

supramolecular fiber organization [inference]

intermediate filament organization

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
intermediate filament	IBA
neurofilament	IDA	10221457
cytoplasmic ribonucleoprotein granule	ISO
cytoplasmic ribonucleoprotein granule	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

synapse [inference]

myelin sheath

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

postsynapse

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

neurofilament

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21689717
protein-containing complex binding	ISO
structural constituent of postsynaptic intermediate filament cytoskeleton	IDA	25869803
structural constituent of postsynaptic intermediate filament cytoskeleton	IMP	25869803
structural constituent of postsynaptic intermediate filament cytoskeleton	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton [inference]

structural constituent of postsynaptic intermediate filament cytoskeleton

structural constituent of synapse [inference]

structural constituent of postsynapse [inference]

structural constituent of postsynaptic intermediate filament cytoskeleton

binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-internexin

Functional Category

K: Transcription
L: Replication, recombination and repair
V: Defense mechanisms

Displaying **all 2** entries
Gene Ontology
intermediate filament organization
structural constituent of postsynaptic intermediate filament cytoskeleton

Displaying **all 3** entries
InterPro
Intermediate filament head, DNA-binding domain
Intermediate filament protein, conserved site
Intermediate filament, rod domain

Ortholog

Displaying entries **1 - 10** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9118	Xenbase:XB-GENE-492716	HUMAN02822
Rattus norvegicus	24503		RATNO21093
Danio rerio	30230		DANRE16649
Xenopus tropicalis	226180	Xenbase:XB-GENE-492716
Ciona intestinalis	445691		CIOIN10748
Pan troglodytes	450709		PANTR01481
Canis lupus familiaris	486869		CANLF11442
Bos taurus	532236		BOVIN21457
Monodelphis domestica	100022560		MONDO06937
Sus scrofa	100153400		PIGXX08431