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internexin neuronal intermediate filament protein, alpha

Summary

Gene Symbol

Ina

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

226180

PubChem

226180

Alliance of Genome Resources

MGI:96568

Annotation

Keyword

Acetylation
Coiled coil
Developmental protein
Differentiation
Direct protein sequencing
Glycoprotein
Intermediate filament
Neurogenesis
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P46660	66 kDa neurofilament protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nervous system development	IEA
cell differentiation	IEA
intermediate filament cytoskeleton organization	IMP	14561875
intermediate filament organization	IBA
neurofilament cytoskeleton organization	IGI	10350642

GO Hierarchy

biological process

cellular process [inference]

intermediate filament-based process [inference]

intermediate filament cytoskeleton organization

cellular developmental process [inference]

cell differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

intermediate filament cytoskeleton organization

postsynaptic cytoskeleton organization [inference]

postsynaptic intermediate filament cytoskeleton organization

supramolecular fiber organization [inference]

intermediate filament organization

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

response to leukemia inhibitory factor [inference]

cellular response to leukemia inhibitory factor

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to leukemia inhibitory factor

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

postsynaptic modulation of chemical synaptic transmission

Displaying entries **6 - 10** of 14 in total

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GO Term	Evidence Code	PMID
myelin sheath	HDA	17634366
Schaffer collateral - CA1 synapse	IDA	25869803
Schaffer collateral - CA1 synapse	IMP	25869803
postsynapse	ISO
postsynapse	IDA	25869803

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

synapse [inference]

myelin sheath

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

intermediate filament cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

postsynaptic cytoskeleton [inference]

postsynaptic intermediate filament cytoskeleton

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

postsynaptic specialization, intracellular component [inference]

postsynaptic density, intracellular component

postsynapse

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

intermediate filament

neurofilament

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21689717
protein-containing complex binding	ISO
structural constituent of postsynaptic intermediate filament cytoskeleton	IDA	25869803
structural constituent of postsynaptic intermediate filament cytoskeleton	IMP	25869803
structural constituent of postsynaptic intermediate filament cytoskeleton	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of cytoskeleton [inference]

structural constituent of postsynaptic intermediate filament cytoskeleton

structural constituent of synapse [inference]

structural constituent of postsynapse [inference]

structural constituent of postsynaptic intermediate filament cytoskeleton

binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Keratin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
intermediate filament organization

Displaying 1 entry
InterPro
Intermediate filament, rod domain

Ortholog

Displaying entries **21 - 30** of 64 in total

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Species	Gene ID	Orthologous MAtrix
Cavia porcellus	100726037	CAVPO06079
Sarcophilus harrisii	100915448	SARHA07252
Otolemur garnettii	100957106	OTOGA14203
Pan paniscus	100993171	PANPA05435
Felis catus	101085925	FELCA26858
Gorilla gorilla gorilla	101139616	GORGO00803
Oryzias latipes	101175297	ORYLA00759
Tursiops truncatus	101329064	TURTR14051
Octodon degus	101569051	OCTDE09272
Jaculus jaculus	101600048	JACJA11036