GlyCosmos Portal

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GO Term	Evidence Code	PMID
protein binding	IPI	25107909
protein serine kinase activity	IEA
metal ion binding	IEA
protein serine/threonine kinase activity	IBA ISO
identical protein binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone H2AS1 kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H2AS1 kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

serine/threonine-protein kinase MRCK alpha

Functional Category

J: Translation, ribosomal structure and biogenesis
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actomyosin structure organization
cytoskeleton organization
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity

Displaying **all 4** entries
InterPro
Citron homology (CNH) domain
KELK-motif containing domain
Myotonic dystrophy protein kinase, coiled coil
Protein kinase domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0060669	cerebral cavernous malformation	Alliance of Genome Resources
DOID:14227	azoospermia	Alliance of Genome Resources

Ortholog

Displaying entries **91 - 100** of **116** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Corvus moneduloides	116441411		CORMO17810
Chelonoidis abingdonii	116835409		CHEAB10576
Rattus rattus	116910880	10117_0:003d88
Rhinolophus ferrumequinum	117018475		RHIFE03456
Arvicanthis niloticus	117721431	61156_0:003a65
Scophthalmus maximus	118289774		SCOMX17124
Onychomys torridus	118592750	38674_0:0032e9
Balaenoptera musculus	118901860		BALMU24786
Arvicola amphibius	119827377	1047088_0:0041b4
Microtus oregoni	121435848	111838_0:004b43

GlyTouCan

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements