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CDC42 binding protein kinase alpha

Summary

Gene Symbol

Cdc42bpa

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

226751

PubChem

226751

Alliance of Genome Resources

MGI:2441841

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Coiled coil
Cytoplasm
Phosphoprotein
Proteomics identification
Reference proteome
Serine/threonine-protein kinase
Zinc-finger

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q3UU96	CDC42-binding protein kinase alpha
H7BX44	CDC42-binding protein kinase alpha
E9PVY0	CDC42-binding protein kinase alpha
A0A1D5RLQ9	CDC42-binding protein kinase alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization	IMP	15882626
chromatin remodeling	IEA
protein phosphorylation	ISO
cytoskeleton organization	ISO
nuclear migration	IMP	15882626

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

actin filament-based process [inference]

actin cytoskeleton organization

actomyosin structure organization

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cell motility [inference]

cell migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization

microtubule cytoskeleton organization

actin cytoskeleton organization

actomyosin structure organization

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

nuclear migration

establishment of localization in cell [inference]

intracellular transport [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

organelle localization [inference]

nucleus localization [inference]

nuclear migration

establishment of organelle localization [inference]

nuclear migration

cellular localization [inference]

intracellular transport [inference]

nuclear migration

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
cytoplasm	IEA
cytoskeleton	IBA
cell-cell junction	ISO
lamellipodium	IDA	25107909

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

anchoring junction [inference]

cell-cell junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

Displaying entries **11 - 15** of 30 in total

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GO Term	Evidence Code	PMID
ATP binding	IEA
zinc ion binding	IEA
histone H3S10 kinase activity	IEA
histone H3T11 kinase activity	IEA
histone H3T6 kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

protein serine kinase activity

histone modifying activity [inference]

histone kinase activity [inference]

histone H2A kinase activity [inference]

histone H3 kinase activity [inference]

histone H4 kinase activity [inference]

histone H4S1 kinase activity

histone H2B kinase activity [inference]

histone H2AX kinase activity [inference]

histone H2AXS139 kinase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

magnesium ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MRCK alpha

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actomyosin structure organization
cytoskeleton organization
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity

Displaying entries **1 - 10** of 14 in total

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InterPro
AGC-kinase, C-terminal
C1-like domain superfamily
CRIB domain
Citron homology (CNH) domain
KELK-motif containing domain
Myotonic dystrophy protein kinase, coiled coil
PH-like domain superfamily
Pleckstrin homology domain
Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
Protein kinase domain

Ortholog

Displaying entries **41 - 50** of 82 in total

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Species	Gene ID	Orthologous MAtrix
Pelodiscus sinensis	102460743	PELSI12181
Vicugna pacos	102545163	VICPA06152
Astyanax mexicanus	103041576	ASTMX08122
Callorhinchus milii	103187627	CALMI37158
Chlorocebus sabaeus	103229982	CHLSB11883
Carlito syrichta	103271840	CARSF09024
Ursus maritimus	103666984	URSMA07214
Nannospalax galili	103725093	NANGA20861
Serinus canaria	103821304	SERCA17779
Rhinopithecus roxellana	104676957	RHIRO21388