GlyCosmos Portal

Submissions

eukaryotic translation initiation factor 5B

Summary

Gene Symbol

Eif5b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

226982

PubChem

226982

Alliance of Genome Resources

MGI:2441772

Annotation

Keyword

Cytoplasm
GTP-binding
Hydrolase
Initiation factor
Metal-binding
Phosphoprotein
Protein biosynthesis
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q05D44	Translation initiation factor IF-2
Q6A002

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
translational initiation	IBA
translational initiation	IEA
regulation of translational initiation	ISO
regulation of translational initiation	IEA
ribosome assembly	ISO

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

translational initiation

cellular process [inference]

cellular metabolic process [inference]

translational initiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

ribosome assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

ribosome assembly

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of nitrogen compound metabolic process [inference]

regulation of amide metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of translation [inference]

regulation of translational initiation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

post-transcriptional regulation of gene expression [inference]

regulation of translation [inference]

regulation of translational initiation

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasm	ISO
cytoplasm	IBA
cytoplasm	IEA
synapse	EXP	25211037
synapse	IDA	25211037

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

cell junction [inference]

synapse

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
tRNA binding	ISO
tRNA binding	IEA
translation initiation factor activity	ISO
translation initiation factor activity	IBA
translation initiation factor activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

GTPase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

GTP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding [inference]

tRNA binding

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

GTP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

translation regulator activity [inference]

translation regulator activity, nucleic acid binding [inference]

translation factor activity, RNA binding [inference]

translation initiation factor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Translation Initiation Factor

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
GTP binding

Displaying **all 8** entries
InterPro
Elongation factor Tu-type domain
P-loop containing nucleoside triphosphate hydrolase
Small GTP-binding protein domain
Translation initiation factor IF- 2, domain 3
Translation initiation factor IF- 2
Translation initiation factor IF-2, domain 3 superfamily
Translation protein, beta-barrel domain superfamily
Translational (tr)-type GTP-binding domain

Rhea

RHEA:19669

H₂O + GTP

H⁺ + phosphate + GDP

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of 70 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9669	Xenbase:XB-GENE-6258156	HUMAN64023
Xenopus tropicalis	226982	Xenbase:XB-GENE-6258156
Rattus norvegicus	308306		RATNO44046
Pan troglodytes	459443		PANTR28310
Canis lupus familiaris	474556		CANLF01762
Bos taurus	532850		BOVIN02025
Danio rerio	561194		DANRE17440
Macaca mulatta	714129		MACMU08653
Oryctolagus cuniculus	100008656		RABIT08307
Monodelphis domestica	100014602		MONDO32710

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements