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zona pellucida 3 receptor

Summary

Gene Symbol

Zp3r

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22789

PubChem

22789

Alliance of Genome Resources

MGI:104965

Annotation

Keyword

Disulfide bond
Proteomics identification
Receptor
Reference proteome
Signal
Sushi

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q0VET1
G3X970

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
regulation of opsonization	ISO
binding of sperm to zona pellucida	IDA IMP ISO	11417900 21880732 7604284
response to symbiotic bacterium	ISO
negative regulation of complement activation, classical pathway	IBA ISO
single fertilization	IDA	9890753

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

leukocyte mediated immunity [inference]

lymphocyte mediated immunity [inference]

T cell mediated immunity

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

cellular process [inference]

cell recognition [inference]

cell-cell recognition [inference]

sperm-egg recognition [inference]

binding of sperm to zona pellucida

reproductive process [inference]

fertilization [inference]

single fertilization

sperm-egg recognition [inference]

binding of sperm to zona pellucida

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to stimulus [inference]

immune response [inference]

adaptive immune response [inference]

adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

T cell mediated immunity

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to symbiont [inference]

response to symbiotic bacterium

response to bacterium [inference]

response to symbiotic bacterium

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of immune effector process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of leukocyte mediated immunity [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of lymphocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of opsonization

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune effector process [inference]

negative regulation of leukocyte mediated immunity [inference]

negative regulation of lymphocyte mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of response to stimulus [inference]

negative regulation of response to stimulus [inference]

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of immune response [inference]

regulation of adaptive immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

regulation of B cell mediated immunity [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of immunoglobulin mediated immune response [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response [inference]

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

regulation of complement activation [inference]

regulation of complement activation, classical pathway [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

negative regulation of immune response [inference]

negative regulation of adaptive immune response [inference]

negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains [inference]

negative regulation of B cell mediated immunity [inference]

negative regulation of immunoglobulin mediated immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of humoral immune response [inference]

negative regulation of humoral immune response mediated by circulating immunoglobulin [inference]

negative regulation of complement activation, classical pathway

negative regulation of complement activation [inference]

negative regulation of complement activation, classical pathway

regulation of cellular process [inference]

regulation of opsonization

Displaying entries **6 - 9** of 9 in total

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GO Term	Evidence Code	PMID
cell body	IDA	21880732
acrosomal vesicle	EXP IDA	16540102 21640725 23976951 25605614 9890753
extracellular space	IBA ISO
zona pellucida receptor complex	IDA	21880732

GO Hierarchy

cellular component

protein-containing complex [inference]

zona pellucida receptor complex

cellular anatomical entity [inference]

extracellular space

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

outer acrosomal membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

acrosomal lumen

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen [inference]

acrosomal lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

acrosomal lumen

acrosomal matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

secretory vesicle [inference]

secretory granule [inference]

acrosomal vesicle

cell body

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	11417900 7604284

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Complement decay-accelerating factor

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Sushi/SCR/CCP domain
Sushi/SCR/CCP superfamily

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0080600	COVID-19	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 45 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Jaculus jaculus	101603229	51337_0:0004b1
Heterocephalus glaber	101720618	10181_0:00343c
Heterocephalus glaber	101722923	10181_0:0027f6
Mesocricetus auratus	101827079	10036_0:004f65
Ictidomys tridecemlineatus	101965450	43179_0:004bf5
Microtus ochrogaster	101982850	79684_0:000ec5
Chinchilla lanigera	102029362	34839_0:0004de	CHILA01762
Peromyscus maniculatus bairdii	102915133	230844_0:003565
Dipodomys ordii	105986441	10020_0:001c65
Marmota marmota marmota	107140314	9994_0:001ffd

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements