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5'-3' exoribonuclease 2

Summary

Gene Symbol

XRN2

Organism

Homo sapiens (human)

External Links

NCBI Gene

22803

PubChem

22803

Alliance of Genome Resources

HGNC:12836

Annotation

Keyword

Acetylation
Alternative splicing
DNA-binding
Exonuclease
Methylation
Nucleus
Phosphoprotein
Reference proteome
Transcription regulation
Transcription termination
Zinc-finger
mRNA processing

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9H0D6	DHM1-like protein
B4DZC3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

1

2

3

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Last »
GO Term	Evidence Code	PMID
nuclear-transcribed mRNA catabolic process	IBA
rRNA processing	TAS
termination of RNA polymerase II transcription	IMP	15565158
RNA processing	TAS	10409438
mRNA processing	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic cyclic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular nitrogen compound catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

nucleic acid metabolic process [inference]

RNA metabolic process

RNA processing

mRNA processing

ncRNA processing [inference]

rRNA processing

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

mRNA metabolic process [inference]

mRNA processing

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing

ncRNA processing [inference]

rRNA processing

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

RNA biosynthetic process [inference]

DNA-templated transcription termination [inference]

termination of RNA polymerase II transcription

heterocycle catabolic process [inference]

nucleobase-containing compound catabolic process [inference]

RNA catabolic process

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

reproductive process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

spermatogenesis

anatomical structure development [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

mRNA catabolic process [inference]

nuclear-transcribed mRNA catabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleus	IBA
nucleoplasm	TAS
nucleoplasm	IDA
nucleolus	IDA	12429849
membrane	HDA	19946888

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

aggresome

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
3'-5'-RNA exonuclease activity	EXP	23482395
transcription termination site sequence-specific DNA binding	IDA	21700224
RNA binding	IBA
RNA binding	HDA	22658674 22681889
nuclease activity	TAS	10409438

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

nuclease activity

exonuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

3'-5' exonuclease activity [inference]

3'-5'-RNA exonuclease activity

5'-3' exonuclease activity

5'-3' RNA exonuclease activity

exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA nuclease activity [inference]

RNA exonuclease activity [inference]

RNA exonuclease activity, producing 5'-phosphomonoesters [inference]

binding [inference]

protein binding

identical protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

transcription regulatory region nucleic acid binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

DNA binding [inference]

double-stranded DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

sequence-specific DNA binding [inference]

sequence-specific double-stranded DNA binding [inference]

transcription cis-regulatory region binding [inference]

transcription termination site sequence-specific DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

5'-3' exoribonuclease A

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
5'-3' RNA exonuclease activity
hydrolase activity
nuclease activity

Displaying **all 3** entries
InterPro
5'-3' exoribonuclease
Xrn1, N-terminal
Xrn1, helical domain

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0080202	adenoid cystic carcinoma	Alliance of Genome Resources
DOID:1324	lung cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	22803	Xenbase:XB-GENE-993157
Mus musculus	24128	Xenbase:XB-GENE-993157	MOUSE35886
Danio rerio	321940		DANRE19678
Rattus norvegicus	362229		RATNO26265
Pan troglodytes	458131		PANTR24479
Canis lupus familiaris	477133		CANLF09250
Bos taurus	517417		BOVIN04588
Macaca mulatta	700934		MACMU01667
Monodelphis domestica	100031372		MONDO08687
Equus caballus	100050094		HORSE21001

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements