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BPI fold containing family B, member 1

Summary

Gene Symbol

Bpifb1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

228801

PubChem

228801

Alliance of Genome Resources

MGI:2137431

Annotation

Keyword

Disulfide bond
Glycoprotein
Innate immunity
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q61114	Long palate, lung and nasal epithelium carcinoma-associated protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
innate immune response in mucosa	ISO
innate immune response in mucosa	IBA
innate immune response in mucosa	IEA
negative regulation of toll-like receptor 4 signaling pathway	ISO
negative regulation of toll-like receptor 4 signaling pathway	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

innate immune response [inference]

innate immune response in mucosa

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

immune response [inference]

organ or tissue specific immune response [inference]

mucosal immune response [inference]

innate immune response in mucosa

innate immune response [inference]

innate immune response in mucosa

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

innate immune response [inference]

innate immune response in mucosa

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of response to external stimulus [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of immune response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of response to stress [inference]

regulation of defense response [inference]

regulation of innate immune response [inference]

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

regulation of pattern recognition receptor signaling pathway [inference]

regulation of toll-like receptor 4 signaling pathway [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of toll-like receptor 4 signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	ISO
extracellular space	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying 1 entry
GO Term	Evidence Code	PMID
lipid binding	IEA

GO Hierarchy

molecular function

binding [inference]

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

BPI fold-containing family B member 1

Functional Category

E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
innate immune response in mucosa
lipid binding
negative regulation of toll-like receptor 4 signaling pathway

Displaying **all 4** entries
InterPro
BPI fold-containing family B member 1
Bactericidal permeability-increasing protein, alpha/beta domain superfamily
Lipid-binding serum glycoprotein, C-terminal
Lipid-binding serum glycoprotein, N-terminal

Ortholog

Displaying entries **1 - 10** of 40 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	92747	HGNC:16108	HUMAN56540
Homo sapiens	228801	HGNC:16108
Bos taurus	282643		BOVIN05103
Pan troglodytes	458178		PANTR24644
Canis lupus familiaris	477194		CANLF09452
Rattus norvegicus	499926	HGNC:16108	RATNO26026
Macaca mulatta	710014		MACMU02895
Sus scrofa	100113426		PIGXX11593
Callithrix jacchus	100406202		CALJA35303
Pongo abelii	100431356		PONAB20301