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ARF GTPase activating protein 1

Summary

Gene Symbol

Arfgap1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

228998

PubChem

228998

Alliance of Genome Resources

MGI:2183559

Annotation

Keyword

Acetylation
Alternative splicing
Cytoplasm
ER-Golgi transport
GTPase activation
Golgi apparatus
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
Zinc-finger

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q6PB94
Q3TGS9
V9GXM1
Q9EPJ9	ADP-ribosylation factor 1 GTPase-activating protein ARF1-directed GTPase-activating protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein transport	IEA
vesicle-mediated transport	IEA
regulation of endocytosis	IDA	24792215
regulation of endocytosis	IBA
regulation of ARF protein signal transduction	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of localization [inference]

regulation of transport [inference]

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

regulation of ARF protein signal transduction

regulation of cellular component organization [inference]

regulation of endocytosis

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

Displaying entry **6 - 6** of 6 in total

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GO Term	Evidence Code	PMID
synapse	IDA	22423108

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

cell junction [inference]

synapse

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

postsynaptic specialization [inference]

postsynaptic density

Displaying **all 5** entries
GO Term	Evidence Code	PMID
GTPase activator activity	ISO	22423108
GTPase activator activity	IBA
protein binding	IPI	22363216 22423108
zinc ion binding	IEA
metal ion binding

GO Hierarchy

molecular function

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

nucleoside-triphosphatase regulator activity [inference]

GTPase regulator activity [inference]

GTPase activator activity

molecular function activator activity [inference]

enzyme activator activity [inference]

GTPase activator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

ADP-ribosylation factor GTPase-activating protein 1

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
regulation of ARF protein signal transduction
regulation of endocytosis

Displaying **all 3** entries
InterPro
ARFGAP/RecO-like zinc finger
Arf GTPase activating protein
ArfGAP domain superfamily

Ortholog

Displaying entries **31 - 40** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Mustela putorius furo	101688493	MUSPF10321
Ficedula albicollis	101816275	FICAL08066
Melopsittacus undulatus	101869650	MELUD11956
Chrysemys picta bellii	101937604	CHRPI13344
Ictidomys tridecemlineatus	101964553	ICTTR02734
Chinchilla lanigera	102016415	CHILA22490
Capra hircus	102183080	CAPHI03809
Myotis lucifugus	102428154	MYOLU18137
Pelodiscus sinensis	102454915	PELSI12589
Astyanax mexicanus	103031499	ASTMX05339