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MIRAGE
arylsulfatase G

Summary
Gene Symbol
  • ARSG
Aliases
  • KIAA1001
Organism
Homo sapiens (human)
NCBI Gene
22901
HGNC
24102
KEGG Gene ID
hsa:22901
PubChem
22901
Alliance of Genome Resources
Annotation
Keyword
  • Calcium
  • Disease variant
  • Disulfide bond
  • Glycoprotein
  • Hydrolase
  • Lysosome
  • Metal-binding
  • Reference proteome
  • Retinitis pigmentosa
  • Signal
  • Usher syndrome
Proteins
Displaying 1 entry
UniProt Protein Name
Q96EG1
  • N-sulfoglucosamine-3-sulfatase
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 7 in total
GO Term Evidence Code PMID
sulfur compound metabolic process
lysosome organization
glial cell differentiation
gene expression
homeostasis of number of cells
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
arylsulfatase I
Functional Category
  • E: Amino acid transport and metabolism
  • Q: Secondary metabolites biosynthesis, transport and catabolism
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
hydrolase activity
sulfuric ester hydrolase activity
Displaying all 3 entries
InterPro
Alkaline-phosphatase-like, core domain superfamily
Sulfatase, N-terminal
Sulfatase, conserved site
KEGG BRITE Database
Orthology
K12381
Name
arylsulfatase G [EC:3.1.6.-]
References
Rhea

RHEA:17261

an aryl sulfate + H2O
H+ + sulfate + a phenol
Enzyme
PMID
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0050439 Usher syndrome
The Human Phenotype Ontology
Displaying entries 1 - 10 of 24 in total
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0000375 Abnormal cochlea morphology
HP:0000407 Sensorineural hearing impairment
HP:0000408 Progressive sensorineural hearing impairment
HP:0000483 Astigmatism
HP:0000512 Abnormal electroretinogram
HP:0000518 Cataract
HP:0000546 Retinal degeneration
HP:0000572 Visual loss
HP:0000575 Scotoma
Displaying all 2 entries
Disease ID Disease Name
ORPHA:231183
  • Usher syndrome type 3
  • retinitis pigmentosa-deafness syndrome
OMIM:618144
  • Usher syndrome, type 4
PubChem Disease
MedGen Diseases
OMIM Phenotypes
KEGG Diseases
Gene-Disease-Co-Occurrences-in-Literature (PubChem)
LIPID MAPS Gene / Proteome Database
LMPD ID
LMP005434
Gene Name
arylsulfatase G
Ortholog
Displaying entries 21 - 30 of 79 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100716143 CAVPO19580
100751256 CRIGR07263
100964344 OTOGA14845
100968064 PANPA17797
101021845 PAPAN14432
101032857 SAIBB19725
101093311 FELCA32779
101149965 GORGO33505
101330514 TURTR09361
101569323 OCTDE07930
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025