GlyCosmos Portal

Submissions

spartin

Summary

Gene Symbol

Spart

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

229285

PubChem

229285

Alliance of Genome Resources

MGI:2139806

Annotation

Keyword

Acetylation
Alternative splicing
Cytoplasm
Isopeptide bond
Lipid degradation
Lipid droplet
Lipid transport
Lipid-binding
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8R1X6
Q3TVW1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 19 in total

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GO Term	Evidence Code	PMID
cytokinesis	IMP	22619377
lipid transport	ISS
abscission	ISO
lipid catabolic process	IEA
BMP signaling pathway	IMP	22619377

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

organic substance catabolic process [inference]

lipid catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

cell growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

cell cycle process [inference]

cytokinesis

cytokinetic process [inference]

mitotic cytokinetic process [inference]

midbody abscission

mitotic cell cycle process [inference]

mitotic cytokinetic process [inference]

midbody abscission

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

cell division

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy [inference]

lipophagy

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

lipid droplet organization

membrane organization [inference]

midbody abscission

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

neuromuscular process

developmental process [inference]

abscission

anatomical structure development [inference]

tissue development [inference]

connective tissue development [inference]

adipose tissue development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

developmental growth [inference]

developmental cell growth [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

developmental growth involved in morphogenesis [inference]

collateral sprouting [inference]

collateral sprouting in absence of injury

localization [inference]

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of growth [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of extent of cell growth [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of developmental growth [inference]

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of developmental growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell development [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cell differentiation [inference]

negative regulation of cell development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cellular component organization [inference]

regulation of cell growth [inference]

negative regulation of cell growth [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of extent of cell growth [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

regulation of cell projection organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of axonogenesis [inference]

regulation of collateral sprouting [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of collateral sprouting in absence of injury [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of cellular component organization [inference]

negative regulation of cell projection organization [inference]

negative regulation of neuron projection development [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

negative regulation of nervous system development [inference]

negative regulation of neurogenesis [inference]

negative regulation of axonogenesis [inference]

negative regulation of collateral sprouting [inference]

negative regulation of collateral sprouting in absence of injury

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of mitochondrial membrane potential

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
mitochondrial outer membrane	ISO
lipid droplet	IDA	21707618
cytosol	ISO
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

cell junction [inference]

synapse

midbody

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	21707618
lipid binding	ISS
ubiquitin protein ligase binding	ISO
ubiquitin protein ligase binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

lipid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Spartin

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell division

Displaying **all 4** entries
InterPro
MIT domain superfamily
MIT domain
Senescence/spartin-associated, C-terminal
Spartin-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0050886	Troyer syndrome	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements