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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
sirtuin 2
Summary
- Gene Symbol
-
- SIRT2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Autophagy
- Cell membrane
- Cell projection
- Chromosome
- Cytoskeleton
- Differentiation
- Innate immunity
- Meiosis
- Metal-binding
- Microtubule
- Mitosis
- NAD
- Neurodegeneration
- Neurogenesis
- Nucleus
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transcription regulation
- Transferase
- Ubl conjugation
- Zinc
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A0A0MRF5 |
|
| Q8IXJ6 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of myelination | ||
| regulation of exit from mitosis | ||
| mitotic nuclear membrane reassembly | ||
| cellular lipid catabolic process | ||
| negative regulation of transcription by RNA polymerase II |
GO Hierarchy
- regulation of myelination
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of catabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of nitrogen compound metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of lipid metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of protein metabolic process [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of developmental process [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of multicellular organismal process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| NAD+ ADP-ribosyltransferase activity | ||
| transcription factor binding | ||
| NAD-dependent histone deacetylase activity | ||
| zinc ion binding | ||
| chromatin binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2237 | hepatitis | |
| DOID:2348 | arteriosclerotic cardiovascular disease | |
| DOID:2349 | arteriosclerosis | |
| DOID:235 | colonic benign neoplasm | |
| DOID:2377 | multiple sclerosis | |
| DOID:2394 | ovarian cancer | |
| DOID:2513 | basal cell carcinoma | |
| DOID:2841 | asthma | |
| DOID:2848 | obsolete melancholia | |
| DOID:2871 | endometrial carcinoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100189919 | PONAB14186 | ||
| 112928407 | VULVU23070 | ||
| 123784455 | URSAM25784 | ||
| 101682580 | MUSPF03289 | ||
| 101099513 | FELCA34732 | ||
| 118885507 | BALMU16631 | ||
| 100660519 | LOXAF03471 | ||
| 100125964 | PIGXX27798 | ||
| 102181151 | CAPHI08967 | ||
| 101113169 | SHEEP05367 |
