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Guidelines

MIRAGE

centrosomal protein 152

Summary

Gene Symbol

CEP152

Organism

Homo sapiens (human)

External Links

NCBI Gene

22995

PubChem

22995

Alliance of Genome Resources

HGNC:29298

Annotation

Keyword

3D-structure
Alternative splicing
Cilium biogenesis/degradation
Coiled coil
Cytoskeleton
Disease variant
Dwarfism
Intellectual disability
Phosphoprotein
Primary microcephaly
Proteomics identification
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3B7A2
O94986

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
centriole replication	ISS
centriole replication	IDA	21059844
centriole replication	IBA
cell projection organization	IEA
centrosome duplication	IMP	20852615

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule organizing center organization [inference]

centriole assembly [inference]

centriole replication

de novo centriole assembly [inference]

de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

cell cycle process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

centriole assembly [inference]

centriole replication

de novo centriole assembly [inference]

de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

centriole assembly [inference]

centriole replication

de novo centriole assembly [inference]

de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

cell projection organization

microtubule organizing center organization [inference]

centriole assembly [inference]

centriole replication

de novo centriole assembly [inference]

de novo centriole assembly involved in multi-ciliated epithelial cell differentiation

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
pericentriolar material	IDA	26337392
nucleoplasm	IDA
centrosome	IDA	21131973 21399614 35849559
centrosome	IBA
centriole	IDA	22020124 26337392 32060285

GO Hierarchy

cellular component

protein-containing complex [inference]

procentriole replication complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

procentriole

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	20852615 21059844 21131973 24997597 26188084 26297806 26496610 26638075 35709258 35849559
protein kinase binding	IPI	20852615 21059844

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Centrosomal protein

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0070012	Seckel syndrome 5	Alliance of Genome Resources
DOID:0070292	primary autosomal recessive microcephaly 9	Alliance of Genome Resources

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025