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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
WD repeat and FYVE domain containing 3
Summary
- Gene Symbol
-
- WDFY3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Autophagy
- Cell projection
- Cytoplasm
- Developmental protein
- Disease variant
- Lipid-binding
- Membrane
- Nucleus
- Phosphoprotein
- Primary microcephaly
- Reference proteome
- Repeat
- WD repeat
- Zinc-finger
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8IZQ1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| aggrephagy |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| nuclear membrane | ||
| membrane | ||
| autophagosome membrane | ||
| perikaryon | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| metal ion binding | ||
| 1-phosphatidylinositol binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- FYVE zinc finger
- Functional Category
-
- C: Energy production and conversion
- E: Amino acid transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| metal ion binding |
| InterPro |
|---|
| FYVE zinc finger |
| Zinc finger, FYVE-related |
| Zinc finger, FYVE/PHD-type |
| Zinc finger, RING/FYVE/PHD-type |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060041 | autism spectrum disorder | |
| DOID:0070295 | primary autosomal dominant microcephaly 18 | |
| DOID:2935 | Chediak-Higashi syndrome |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 33819 | FB:FBgn0043362 | |||
| 72145 | MGI:1096875 | MOUSE43271 | ||
| 178220 | WB:WBGene00007752 | |||
| 305164 | RGD:1307097 | RATNO08629 | ||
| 461201 | 9598_0:001575 | PANTR33586 | ||
| 487841 | CANLF13040 | |||
| 537096 | BOVIN31790 | |||
| 568432 | ZFIN:ZDB-GENE-070705-153 | DANRE35646 | ||
| 706535 | MACMU37706 | |||
| 850398 | SGD:S000000628 |
