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myosin XVI

Summary

Gene Symbol

MYO16

Organism

Homo sapiens (human)

External Links

NCBI Gene

23026

PubChem

23026

Alliance of Genome Resources

HGNC:29822

Annotation

Keyword

ANK repeat
ATP-binding
Actin-binding
Alternative splicing
Cytoplasm
Myosin
Phosphoprotein
Proteomics identification
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
F8W883
Q9Y6X6	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 3 Unconventional myosin-16

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
negative regulation of cell population proliferation	ISS	17029291
cerebellum development	ISS	11588169
phosphatidylinositol 3-kinase/protein kinase B signal transduction	IBA
neuron projection morphogenesis	IBA
negative regulation of G1/S transition of mitotic cell cycle	ISS	17029291

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis

anatomical structure development [inference]

cerebellum development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

phosphatidylinositol 3-kinase/protein kinase B signal transduction

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle process [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of cell cycle G1/S phase transition [inference]

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

regulation of G1/S transition of mitotic cell cycle [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of cell cycle G1/S phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of G1/S transition of mitotic cell cycle

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleoplasm	IDA	17029291
nucleoplasm	IBA
cytoplasm	ISS	11588169
plasma membrane	ISS	11588169 17029291
myosin complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

myosin complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

perinuclear region of cytoplasm

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoskeletal motor activity	IEA
protein binding	IPI	25902260
ATP binding	IEA
protein phosphatase binding	IBA
actin filament binding	ISS	11588169

GO Hierarchy

molecular function

cytoskeletal motor activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

phosphatase binding [inference]

protein phosphatase binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

protein-containing complex binding [inference]

actin filament binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

myosin XVI

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
ATP binding
actin binding
actin filament binding
cytoskeletal motor activity
negative regulation of G1/S transition of mitotic cell cycle
neuron projection morphogenesis
nucleotide binding
protein phosphatase binding

Displaying **all 8** entries
InterPro
Ankyrin repeat-containing domain superfamily
Ankyrin repeat
IQ motif, EF-hand binding site
Kinesin motor domain superfamily
Myosin head, motor domain
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, C-terminal domain
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter, N-terminal
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **41 - 50** of 55 in total

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Species	Gene ID	Orthologous MAtrix
Equus asinus asinus	106838199	EQUAS10662
Kryptolebias marmoratus	108232482	KRYMA06207
Ictalurus punctatus	108266992	ICTPU31238
Pygocentrus nattereri	108431490	PYGNA14387
Rhinopithecus bieti	108527032	RHIBE07229
Cyprinus carpio carpio	109088153	CYPCA50492
Crocodylus porosus	109306323	CROPO03841
Seriola dumerili	111218566	SERDU02982
Amphiprion ocellaris	111566601	AMPOC10279
Vulpes vulpes	112927498	VULVU22050