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lysine demethylase 1A
Summary
- Gene Symbol
-
- KDM1A
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Chromatin regulator
- Chromosome
- Coiled coil
- Developmental protein
- Direct protein sequencing
- Disease variant
- FAD
- Isopeptide bond
- Nucleus
- Oxidoreductase
- Phosphoprotein
- Reference proteome
- Repressor
- Transcription regulation
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O60341 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| negative regulation of transcription by RNA polymerase II | ||
| positive regulation of neuroblast proliferation | ||
| regulation of transcription by RNA polymerase II | ||
| protein demethylation |
GO Hierarchy
biological process
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of protein metabolic process [inference]
regulation of RNA metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of signaling [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of signaling [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of response to stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of signal transduction [inference]
negative regulation of signal transduction [inference]
regulation of intracellular signal transduction [inference]
regulation of apoptotic signaling pathway [inference]
negative regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of programmed cell death [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| p53 binding | ||
| chromatin binding | ||
| chromatin binding | ||
| transcription coactivator activity | ||
| transcription coactivator activity |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Lysine-specific histone demethylase
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- Q: Secondary metabolites biosynthesis, transport and catabolism
| Gene Ontology |
|---|
| oxidoreductase activity |
| InterPro |
|---|
| Amine oxidase |
| FAD/NAD(P)-binding domain superfamily |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 115544038 | GADMO49984 | ||
| 115565925 | SPAAU03940 | ||
| 115615991 | STRHB12514 | ||
| 115616143 | STRHB12559 | ||
| 116455176 | CORMO11498 | ||
| 116826277 | CHEAB28420 | ||
| 117027824 | RHIFE01870 | ||
| 118905801 | BALMU22350 | ||
| 122226991 | PANLE09993 |
