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Guidelines

MIRAGE

kinesin family member 21B

Summary

Gene Symbol

KIF21B

Organism

Homo sapiens (human)

External Links

NCBI Gene

23046

PubChem

23046

Alliance of Genome Resources

HGNC:29442

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Coiled coil
Cytoplasmic vesicle
Cytoskeleton
Microtubule
Motor protein
Phosphoprotein
Reference proteome
Repeat
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q2UVF0
O75037

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
microtubule-based movement	IBA

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA
kinesin complex	IBA
microtubule	IBA
dendrite	IEA
growth cone	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

cellular anatomical entity [inference]

cytoplasm

site of polarized growth [inference]

growth cone

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

dendrite

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
microtubule motor activity	IBA
protein binding	IPI	32296183
ATP binding	IEA
microtubule binding	IBA
ATP hydrolysis activity	IBA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Kinesin

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
nucleotide binding

Displaying **all 5** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	16564	FB:FBgn0032243
Mus musculus	16565	Xenbase:XB-GENE-981200	MOUSE30165
Xenopus tropicalis	23046	Xenbase:XB-GENE-981200
Drosophila melanogaster	55605	FB:FBgn0032243
Rattus norvegicus	289397		RATNO06546
Pan troglodytes	457613		PANTR23322
Canis lupus familiaris	490245		CANLF17055
Danio rerio	570502		DANRE02995
Macaca mulatta	710792		MACMU25166
Monodelphis domestica	100013603		MONDO11673

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Supported by JST NBDC Grant Number JPMJND2204

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Last updated: March 31, 2025