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PDS5 cohesin associated factor B

Summary

Gene Symbol

PDS5B

Organism

Homo sapiens (human)

External Links

NCBI Gene

23047

PubChem

23047

Alliance of Genome Resources

HGNC:20418

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Repeat

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NTI5	Androgen-induced proliferation inhibitor Androgen-induced prostate proliferative shutoff-associated protein AS3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
DNA repair	IBA
mitotic sister chromatid cohesion	IMP	15855230
mitotic sister chromatid cohesion	IBA
cell population proliferation	TAS	10963680
negative regulation of cell population proliferation	IDA	10963680

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular process [inference]

cell population proliferation

cell cycle process [inference]

sister chromatid cohesion [inference]

mitotic sister chromatid cohesion

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

DNA repair

cell division

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

sister chromatid cohesion [inference]

mitotic sister chromatid cohesion

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of cellular process [inference]

regulation of cell population proliferation

negative regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
chromosome, centromeric region	TAS
chromatin	IDA	16682347
chromatin	IBA
nucleus	ISS
nucleus	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

chromatin

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

chromosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosome

chromosomal region [inference]

chromosome, centromeric region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
DNA binding	IDA	19412548
protein binding	IPI	15837422 15855230 17112726 17113138 17349791 20360068 21111234 22293751 29867216 31665741 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sister chromatid cohesion

Functional Category

G: Carbohydrate transport and metabolism
L: Replication, recombination and repair
M: Cell wall/membrane/envelope biogenesis

Displaying **all 4** entries
Gene Ontology
DNA repair
cell cycle
cell division
mitotic sister chromatid cohesion

Displaying **all 3** entries
InterPro
Armadillo-like helical
Armadillo-type fold
Sister chromatid cohesion protein Pds5

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	23047	Xenbase:XB-GENE-6041340
Saccharomyces cerevisiae S288C	23244	SGD:S000004681
Mus musculus	100710	Xenbase:XB-GENE-6041340	MOUSE44708
Rattus norvegicus	304218		RATNO06018
Pan troglodytes	452530		PANTR07569
Canis lupus familiaris	486014		CANLF09815
Bos taurus	533890		BOVIN03799
Danio rerio	565592		DANRE08903
Macaca mulatta	721999		MACMU16979
Monodelphis domestica	100020670		MONDO24956