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MIRAGE
purinergic receptor P2X, ligand-gated ion channel, 2
Summary
- Gene Symbol
-
- P2rx2
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- ATP-binding
- Alternative splicing
- Cell membrane
- Disulfide bond
- Glycoprotein
- Hearing
- Ligand-gated ion channel
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q8K3P1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to hypoxia | ||
| response to ischemia | ||
| detection of hypoxic conditions in blood by carotid body chemoreceptor signaling | ||
| chemical synaptic transmission | ||
| neuromuscular synaptic transmission |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| terminal bouton | ||
| dendritic spine | ||
| receptor complex | ||
| receptor complex | ||
| presynaptic active zone membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cadmium ion binding | ||
| cobalt ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- P2x purinoceptor
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| P2X purinoreceptor extracellular domain superfamily |
| P2X purinoreceptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110567 | autosomal dominant nonsyndromic deafness 41 |
