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stabilin 1

Summary

Gene Symbol

STAB1

Organism

Homo sapiens (human)

External Links

NCBI Gene

23166

PubChem

23166

Alliance of Genome Resources

HGNC:18628

Annotation

Keyword

Alternative splicing
Disease variant
Disulfide bond
EGF-like domain
Glycoprotein
Inflammatory response
Laminin EGF-like domain
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9NY15	Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1 MS-1 antigen

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
receptor-mediated endocytosis	TAS	12077138
inflammatory response	IEA
cell adhesion	NAS	12077138
cell-cell signaling	IDA	12077138
negative regulation of angiogenesis	IMP	12077138

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

cell adhesion

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

defense response to other organism [inference]

defense response to bacterium

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium [inference]

defense response to bacterium

defense response to other organism [inference]

defense response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

receptor-mediated endocytosis

import into cell [inference]

endocytosis [inference]

receptor-mediated endocytosis

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

negative regulation of biological process [inference]

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

negative regulation of developmental process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

negative regulation of angiogenesis

negative regulation of vasculature development [inference]

negative regulation of blood vessel morphogenesis [inference]

negative regulation of angiogenesis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	12077138
endocytic vesicle membrane	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endocytic vesicle membrane

bounding membrane of organelle [inference]

endocytic vesicle membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
low-density lipoprotein particle receptor activity	IDA	12077138
scavenger receptor activity	IDA	12077138
calcium ion binding	IEA
protein binding	IPI	16357325 34968453
hyaluronic acid binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on a sulfur group of donors [inference]

disulfide oxidoreductase activity [inference]

protein-disulfide reductase activity

catalytic activity, acting on a protein [inference]

protein-disulfide reductase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

protein-lipid complex binding [inference]

lipoprotein particle binding [inference]

low-density lipoprotein particle binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

hyaluronic acid binding

cargo receptor activity [inference]

scavenger receptor activity

lipoprotein particle receptor activity [inference]

low-density lipoprotein particle receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

stabilin-2

Functional Category

C: Energy production and conversion
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
hyaluronic acid binding

Displaying **all 6** entries
InterPro
C-type lectin fold
EGF domain
EGF-like domain
FAS1 domain superfamily
FAS1 domain
Link domain

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	23166	ZFIN:ZDB-GENE-050208-554
Mus musculus	192187	ZFIN:ZDB-GENE-050208-554	MOUSE13424
Pan troglodytes	461023		PANTR31311
Bos taurus	505543		BOVIN17701
Danio rerio	570626		DANRE22988
Macaca mulatta	696802		MACMU27859
Equus caballus	100060121		HORSE11793
Taeniopygia guttata	100220158		TAEGU03411
Oryctolagus cuniculus	100346795		RABIT12911
Rattus norvegicus	100363145		RATNO11668

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

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Acknowledgements