lipin 1

Summary
Gene Symbol
  • LPIN1
Aliases
  • KIAA0188
  • phosphatidate phosphatase LPIN1
Organism
Homo sapiens (human)
External Links
NCBI Gene
23175
HGNC
13345
KEGG Gene ID
hsa:23175
PubChem
23175
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Endoplasmic reticulum
  • Fatty acid metabolism
  • Hydrolase
  • Isopeptide bond
  • Membrane
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription regulation
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q14693
  • Lipin-1
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000134324

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K15728
Name
phosphatidate phosphatase LPIN [EC:3.1.3.4]
References
Disease
Disease Ontology
Displaying entries 121 - 130 of 134 in total
DO ID Disease Name Source
DOID:631 fibromyalgia
DOID:633 myositis
DOID:684 hepatocellular carcinoma
DOID:687 hepatoblastoma
DOID:783 end stage renal disease
DOID:784 chronic kidney disease
DOID:811 lipodystrophy
DOID:870 neuropathy
DOID:8991 cervix uteri carcinoma in situ
DOID:9256 colorectal cancer
The Human Phenotype Ontology
Displaying entries 31 - 36 of 36 in total
HPO ID HPO Term
HP:0010969 Abnormality of glycolipid metabolism
HP:0011463 Childhood onset
HP:0011675 Arrhythmia
HP:0012544 Elevated circulating aldolase concentration
HP:0100520 Oliguria
HP:0100614 Myositis
Displaying all 2 entries
Disease ID Disease Name
ORPHA:99845
  • hereditary recurrent myoglobinuria
OMIM:268200
  • myoglobinuria, acute recurrent, autosomal recessive

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024