lipin 1

Summary
Gene Symbol
  • LPIN1
Aliases
  • KIAA0188
  • phosphatidate phosphatase LPIN1
Organism
Homo sapiens (human)
External Links
NCBI Gene
23175
HGNC
13345
KEGG Gene ID
hsa:23175
PubChem
23175
Alliance of Genome Resources
Annotation
Keyword
  • Acetylation
  • Alternative splicing
  • Cytoplasm
  • Endoplasmic reticulum
  • Fatty acid metabolism
  • Hydrolase
  • Isopeptide bond
  • Membrane
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Transcription regulation
  • Ubl conjugation
Proteins
Displaying 1 entry
UniProt Protein Name
Q14693
  • Lipin-1
Gene Ontology (GO)
GO Hierarchy
Human Protein Atlas
ENSG00000134324

soft tissue soft tissue blood blood blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node kidney kidney adrenal gland adrenal gland breast breast duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland nasopharynx nasopharynx tongue tonsil tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder ductus deferens ductus deferens seminal vesicle seminal vesicle seminal vesicle seminal vesicle testis testis epididymis epididymis brain smooth muscle urinary bladder prostate bone marrow skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus cartilage sole of foot sole of foot soft tissue blood blood blood blood blood blood blood blood blood blood blood blood lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lymph node lactating breast lactating breast kidney kidney adrenal gland adrenal gland duodenum stomach small intestine colon rectum appendix esophagus eye eye salivary gland salivary gland salivary gland salivary gland salivary gland salivary gland nasopharynx tongue tonsil tonsil hair skin adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue adipose tissue spinal cord oral mucosa lung lung heart bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus bronchus liver pancreas thyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland parathyroid gland spleen gallbladder brain skeletal muscle skeletal muscle skeletal muscle skeletal muscle skeletal muscle thymus thymus smooth muscle urinary bladder vagina ovary ovary fallopian tube fallopian tube endometrium placenta cervix cervix bone marrow cartilage sole of foot sole of foot olfactory region cerebral cortex cerebellum medulla pons midbrain pituitary gland hypothalamus amygdala thalamus choroid plexus choroid plexus corpus callosum basal ganglia substantia nigra dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe dorsal raphe caudate hippocampus retina retina

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

KEGG BRITE Database
Orthology
K15728
Name
phosphatidate phosphatase LPIN [EC:3.1.3.4]
References
Disease
Disease Ontology
Displaying entries 21 - 30 of 134 in total
DO ID Disease Name Source
DOID:0110156 Charcot-Marie-Tooth disease type 2B1
DOID:0110157 Charcot-Marie-Tooth disease type 2J
DOID:0110158 Charcot-Marie-Tooth disease type 2I
DOID:0110159 Charcot-Marie-Tooth disease type 2B
DOID:0110160 Charcot-Marie-Tooth disease axonal type 2T
DOID:0110161 Charcot-Marie-Tooth disease type 2R
DOID:0110163 Charcot-Marie-Tooth disease axonal type 2F
DOID:0110164 Charcot-Marie-Tooth disease type 2D
DOID:0110165 Charcot-Marie-Tooth disease type 2E
DOID:0110166 Charcot-Marie-Tooth disease axonal type 2H
The Human Phenotype Ontology
Displaying entries 1 - 10 of 36 in total
HPO ID HPO Term
HP:0000007 Autosomal recessive inheritance
HP:0000083 Renal insufficiency
HP:0000467 Neck muscle weakness
HP:0001265 Hyporeflexia
HP:0001284 Areflexia
HP:0001315 Reduced tendon reflexes
HP:0001324 Muscle weakness
HP:0001919 Acute kidney injury
HP:0001945 Fever
HP:0002153 Hyperkalemia
Displaying all 2 entries
Disease ID Disease Name
ORPHA:99845
  • hereditary recurrent myoglobinuria
OMIM:268200
  • myoglobinuria, acute recurrent, autosomal recessive
Ortholog
Displaying entries 71 - 73 of 73 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
116441836 CORMO18299
103255848 CARSF19229
115609764 STRHB17217

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024