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MICAL-like 2

Summary

Gene Symbol

Micall2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

231830

PubChem

231830

Alliance of Genome Resources

MGI:2444818

Annotation

Keyword

Cell membrane
Cell projection
Coiled coil
Cytoskeleton
Endosome
LIM domain
Phosphoprotein
Proteomics identification
Reference proteome
Tight junction

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TN34	Junctional Rab13-binding protein Molecule interacting with CasL-like 2
E9PZD2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
actin cytoskeleton organization	IMP	23890175
actin filament polymerization	ISO
actin filament polymerization	IMP	20008558
neuron projection development	ISO
neuron projection development	IMP	20008558

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-substrate adhesion [inference]

substrate adhesion-dependent cell spreading

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rab protein signal transduction

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

actin filament-based process [inference]

actin cytoskeleton organization

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

actin cytoskeleton organization

vesicle organization [inference]

endosome organization [inference]

endosome membrane tubulation

cellular component assembly [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

protein-containing complex assembly [inference]

protein polymerization [inference]

actin filament polymerization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development

cell junction organization [inference]

cell junction assembly [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

cell-cell junction organization [inference]

cell-cell junction assembly [inference]

tight junction assembly [inference]

bicellular tight junction assembly

tight junction organization [inference]

tight junction assembly [inference]

bicellular tight junction assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

actin filament polymerization

membrane organization [inference]

membrane tubulation [inference]

endosome membrane tubulation

supramolecular fiber organization [inference]

actin filament organization [inference]

actin polymerization or depolymerization [inference]

actin filament polymerization

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

endocytic recycling

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling

cellular localization [inference]

intracellular transport [inference]

endosomal transport [inference]

endocytic recycling

localization within membrane [inference]

vesicle-mediated transport to the plasma membrane [inference]

endocytic recycling

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

small GTPase mediated signal transduction [inference]

Ras protein signal transduction [inference]

Rab protein signal transduction

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
stress fiber	IDA	23890175
cytosol
plasma membrane	IDA	18094055
cell-cell junction	IDA	18332111
bicellular tight junction	IDA	16525024

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

tight junction [inference]

bicellular tight junction

actin filament bundle

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	16525024 18332111
filamin binding	ISO
filamin binding	IDA	23890175
small GTPase binding	IPI	18094055 20008558
actinin binding	IPI	23890175

GO Hierarchy

molecular function

binding [inference]

protein binding

cytoskeletal protein binding [inference]

actin binding [inference]

actin filament binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding [inference]

actin filament binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

MICAL-like 2

Functional Category

I: Lipid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
metal ion binding

Displaying **all 4** entries
InterPro
CH domain superfamily
Calponin homology domain
Zinc finger, LIM-type
bMERB domain

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements