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ATPase phospholipid transporting 11B (putative)

Summary

Gene Symbol

ATP11B

Organism

Homo sapiens (human)

External Links

NCBI Gene

23200

PubChem

23200

Alliance of Genome Resources

HGNC:13553

JoGo

ATP11B

TogoVar

ATP11B

Annotation

Keyword

ATP-binding
Endoplasmic reticulum
Endosome
Golgi apparatus
Lipid transport
Magnesium
Metal-binding
Phosphoprotein
Proteomics identification
Reference proteome
Translocase
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B4DKX1
B4E3T1
Q9Y2G3	ATPase IR ATPase class VI type 11B P4-ATPase flippase complex alpha subunit ATP11B

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
monoatomic ion transport	NAS	11790799
ion transport	NAS	11790799
aminophospholipid transport	TAS	11015572
ion transmembrane transport	TAS
monoatomic ion transmembrane transport	TAS

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport

monoatomic ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport

organic substance transport [inference]

lipid transport [inference]

phospholipid transport [inference]

lipid translocation [inference]

phospholipid translocation

organophosphate ester transport [inference]

phospholipid transport [inference]

nitrogen compound transport [inference]

aminophospholipid transport

biological regulation [inference]

regulation of biological quality [inference]

regulation of membrane lipid distribution [inference]

lipid translocation [inference]

phospholipid translocation

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
nuclear inner membrane	NAS	11790799
endoplasmic reticulum	IDA	21914794
endoplasmic reticulum	IBA
Golgi apparatus	IEA
plasma membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

transporter complex [inference]

phospholipid-translocating ATPase complex

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

secretory granule membrane [inference]

azurophil granule membrane

organelle inner membrane [inference]

nuclear inner membrane

nuclear membrane [inference]

nuclear inner membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane [inference]

azurophil granule membrane

endosome membrane [inference]

secretory granule membrane [inference]

azurophil granule membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

recycling endosome

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
protein binding	IPI	21914794 28514442 31571211 33961781
ATP binding	IEA
monoatomic ion transmembrane transporter activity	NAS	11790799
ion transmembrane transporter activity	NAS	11790799

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity [inference]

phosphatidylserine floppase activity

glycerophospholipid flippase activity [inference]

phosphatidylethanolamine flippase activity

intramembrane lipid transporter activity [inference]

ATPase-coupled intramembrane lipid transporter activity

flippase activity [inference]

glycerophospholipid flippase activity [inference]

phosphatidylethanolamine flippase activity

floppase activity [inference]

phosphatidylserine floppase activity

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled intramembrane lipid transporter activity

flippase activity [inference]

glycerophospholipid flippase activity [inference]

phosphatidylethanolamine flippase activity

floppase activity [inference]

phosphatidylserine floppase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ATPase

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
lipid translocation
magnesium ion binding
metal ion binding
nucleotide binding
phospholipid translocation
phospholipid transport

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InterPro
HAD superfamily
HAD-like superfamily
P-type ATPase, A domain superfamily
P-type ATPase, C-terminal
P-type ATPase, N-terminal
P-type ATPase, cytoplasmic domain N
P-type ATPase, haloacid dehalogenase domain
P-type ATPase, phosphorylation site
P-type ATPase, subfamily IV
P-type ATPase, transmembrane domain superfamily