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exocyst complex component 7

Summary

Gene Symbol

EXOC7

Organism

Homo sapiens (human)

External Links

NCBI Gene

23265

PubChem

23265

Alliance of Genome Resources

HGNC:23214

Annotation

Keyword

Alternative splicing
Cell membrane
Coiled coil
Cytoplasm
Epilepsy
Exocytosis
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome

Proteins

Displaying **all 4** entries
UniProt	Protein Name
Q9UPT5	Exocyst complex component Exo70
Q63HP7	Exocyst complex component Exo70
B4DJ07	Exocyst complex component Exo70
B5MCY9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
mitotic cytokinesis	NAS	22420621
exocytosis	IBA
vesicle docking involved in exocytosis	NAS	22420621
regulation of macroautophagy	TAS	21241894
protein transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

exocytosis

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

mitotic cell cycle process [inference]

mitotic cytokinesis

membrane docking [inference]

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

transmembrane transport [inference]

protein transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

membrane fission

vesicle tethering [inference]

vesicle tethering involved in exocytosis

exocytic process [inference]

export from cell [inference]

secretion by cell [inference]

exocytosis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

exocytosis

secretion [inference]

secretion by cell [inference]

exocytosis

transmembrane transport [inference]

protein transmembrane transport

organic substance transport [inference]

protein transport [inference]

protein transmembrane transport

nitrogen compound transport [inference]

protein transport [inference]

protein transmembrane transport

export from cell [inference]

secretion by cell [inference]

exocytosis

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

organelle localization [inference]

organelle localization by membrane tethering [inference]

vesicle docking [inference]

vesicle docking involved in exocytosis

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of entry of bacterium into host cell

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of mitotic cytokinesis [inference]

regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic cytokinetic process

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

positive regulation of cell division [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of mitotic cytokinesis [inference]

regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic cytokinetic process

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

regulation of cytokinetic process [inference]

regulation of mitotic cytokinetic process [inference]

positive regulation of mitotic cytokinetic process

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis [inference]

positive regulation of mitotic cytokinesis [inference]

positive regulation of mitotic cytokinetic process

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
exocyst	NAS	22420621
exocyst	IBA
microtubule organizing center	IDA	18000879
cytosol	TAS
plasma membrane	TAS

GO Hierarchy

cellular component

protein-containing complex [inference]

vesicle tethering complex [inference]

exocyst

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15705715 16148947 16189514 20579884 24169621 25416956 32296183 33961781
phosphatidylinositol-4,5-bisphosphate binding	IEA
protein-macromolecule adaptor activity	IDA	16148947

GO Hierarchy

molecular function

binding [inference]

protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

molecular adaptor activity [inference]

protein-macromolecule adaptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Exocyst complex component

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying 1 entry
Gene Ontology
phosphatidylinositol-4,5-bisphosphate binding

Displaying **all 3** entries
InterPro
Cullin repeat-like-containing domain superfamily
Exocyst complex component Exo70
Exocyst complex subunit Exo70, C-terminal

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	23265	Xenbase:XB-GENE-5829047
Mus musculus	53413		MOUSE03847
Rattus norvegicus	64632		RATNO02414
Danio rerio	406723		DANRE04228
Pan troglodytes	454898		PANTR15484
Bos taurus	505568		BOVIN13947
Macaca mulatta	705801		MACMU14684
Monodelphis domestica	100022282		MONDO10709
Equus caballus	100059108		HORSE03844
Ornithorhynchus anatinus	100091523		ORNAN00194