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anoctamin 5

Summary

Gene Symbol

Ano5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

233246

PubChem

233246

Alliance of Genome Resources

MGI:3576659

Annotation

Keyword

Alternative splicing
Cell membrane
Endoplasmic reticulum
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q75UR0	Gnathodiaphyseal dysplasia 1 protein homolog Transmembrane protein 16E

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane repair	ISS
plasma membrane repair	ISO
chloride transmembrane transport	ISO
chloride transmembrane transport	IBA
chloride transmembrane transport	IEA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization [inference]

plasma membrane repair

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic anion transport [inference]

chloride transport [inference]

chloride transmembrane transport

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport [inference]

chloride transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic anion transmembrane transport [inference]

chloride transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA
plasma membrane	ISO
plasma membrane	IBA
plasma membrane	IEA
vesicle	IDA	17418107

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
intracellular calcium activated chloride channel activity	ISO
intracellular calcium activated chloride channel activity	IDA	23532839
intracellular calcium activated chloride channel activity	IEA
chloride channel activity	IBA
phospholipid scramblase activity	IDA	23532839

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

phospholipid transporter activity [inference]

phospholipid scramblase activity

intramembrane lipid transporter activity [inference]

phospholipid scramblase activity

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic anion transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

monoatomic anion channel activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

salt transmembrane transporter activity [inference]

chloride transmembrane transporter activity [inference]

chloride channel activity

intracellular chloride channel activity [inference]

intracellular calcium activated chloride channel activity

binding [inference]

protein binding [inference]

protein dimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Anoctamin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
chloride channel activity
protein dimerization activity

Displaying **all 3** entries
InterPro
Anoctamin, dimerisation domain
Anoctamin, transmembrane domain
Anoctamin

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0110284	autosomal recessive limb-girdle muscular dystrophy type 2L	Alliance of Genome Resources
DOID:0111533	gnathodiaphyseal dysplasia	Alliance of Genome Resources