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phosphatidylinositol binding clathrin assembly protein

Summary

Gene Symbol

Picalm

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

233489

PubChem

233489

Alliance of Genome Resources

MGI:2385902

Annotation

Keyword

Acetylation
Alternative splicing
Cell membrane
Coated pit
Coiled coil
Cytoplasmic vesicle
Developmental protein
Endocytosis
Golgi apparatus
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q570Z8
Q3TD51
Q7M6Y3	Clathrin assembly lymphoid myeloid leukemia

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **41 - 45** of 68 in total

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GO Term	Evidence Code	PMID
multicellular organismal-level iron ion homeostasis	ISS
multicellular organismal-level iron ion homeostasis	ISO
clathrin-dependent endocytosis	ISO
clathrin-dependent endocytosis	IMP	22539346
clathrin-dependent endocytosis	IBA

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport

endocytosis

receptor-mediated endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosomal transport

transcytosis [inference]

amyloid-beta clearance by transcytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular developmental process [inference]

cell development [inference]

hemopoiesis

cellular localization [inference]

intracellular transport [inference]

endosomal transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

regulation of cellular component size [inference]

regulation of vesicle size

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

clathrin coat assembly

membrane organization [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory

behavior [inference]

learning or memory

transcytosis [inference]

amyloid-beta clearance by transcytosis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

amyloid-beta clearance [inference]

amyloid-beta clearance by transcytosis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

developmental maturation [inference]

synaptic vesicle maturation

anatomical structure development [inference]

cell development [inference]

hemopoiesis

cellular developmental process [inference]

cell development [inference]

hemopoiesis

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

multicellular organismal-level iron ion homeostasis

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular iron ion homeostasis

inorganic ion homeostasis [inference]

multicellular organismal-level chemical homeostasis [inference]

multicellular organismal-level iron ion homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport

endocytosis

receptor-mediated endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

endosomal transport

transcytosis [inference]

amyloid-beta clearance by transcytosis

vesicle-mediated transport in synapse [inference]

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

vesicle cargo loading

intracellular transport [inference]

endosomal transport

import into cell [inference]

endocytosis

receptor-mediated endocytosis

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

establishment of localization in cell [inference]

intracellular transport [inference]

endosomal transport

presynaptic endocytosis [inference]

synaptic vesicle endocytosis

cellular localization [inference]

intracellular transport [inference]

endosomal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of amide metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

regulation of amyloid-beta formation

positive regulation of amyloid-beta formation

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of protein metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of amyloid precursor protein catabolic process

regulation of amyloid-beta formation

positive regulation of amyloid-beta formation

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

regulation of protein transport

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor-mediated endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of synaptic vesicle transport

regulation of synaptic vesicle recycling [inference]

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular localization [inference]

regulation of protein localization

regulation of establishment of protein localization [inference]

regulation of protein transport

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell surface

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

regulation of synaptic vesicle clustering [inference]

positive regulation of synaptic vesicle clustering

regulation of growth [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of amide metabolic process [inference]

positive regulation of amyloid-beta formation

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of protein metabolic process [inference]

positive regulation of amyloid precursor protein catabolic process

positive regulation of amyloid-beta formation

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle recycling [inference]

positive regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle clustering

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell surface

negative regulation of transport [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of cell morphogenesis [inference]

regulation of dendrite extension [inference]

positive regulation of dendrite extension

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of developmental growth [inference]

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of developmental growth [inference]

positive regulation of dendrite extension

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of intracellular signal transduction [inference]

regulation of small GTPase mediated signal transduction [inference]

regulation of Ras protein signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

negative regulation of gene expression

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of cell development [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of small GTPase mediated signal transduction [inference]

positive regulation of Ras protein signal transduction

positive regulation of cell growth [inference]

positive regulation of dendrite extension

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell differentiation [inference]

positive regulation of cell development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell surface

regulation of cellular component organization [inference]

regulation of cell growth [inference]

positive regulation of cell growth [inference]

positive regulation of dendrite extension

regulation of dendrite extension [inference]

positive regulation of dendrite extension

regulation of endocytosis

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor-mediated endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of axonogenesis [inference]

positive regulation of axonogenesis

regulation of synapse organization [inference]

regulation of presynapse organization [inference]

regulation of terminal button organization

negative regulation of cellular component organization [inference]

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of axonogenesis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of cellular localization [inference]

regulation of protein localization

regulation of establishment of protein localization [inference]

regulation of protein transport

negative regulation of protein localization [inference]

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell surface

regulation of protein localization to cell periphery [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to cell periphery [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to membrane [inference]

regulation of protein localization to plasma membrane [inference]

negative regulation of protein localization to plasma membrane

negative regulation of protein localization to membrane [inference]

negative regulation of protein localization to plasma membrane

regulation of protein localization to cell surface [inference]

negative regulation of protein localization to cell surface

regulation of vesicle-mediated transport [inference]

regulation of endocytosis

negative regulation of endocytosis [inference]

negative regulation of receptor-mediated endocytosis

positive regulation of endocytosis [inference]

positive regulation of synaptic vesicle endocytosis

regulation of receptor-mediated endocytosis [inference]

negative regulation of receptor-mediated endocytosis

regulation of synaptic vesicle endocytosis

positive regulation of synaptic vesicle endocytosis

regulation of synaptic vesicle transport

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

regulation of neurogenesis [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

positive regulation of nervous system development [inference]

positive regulation of neurogenesis [inference]

positive regulation of axonogenesis

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of vesicle size

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	PMID
nucleus	ISO
nucleus	IEA
endosome	ISO
early endosome	ISO
early endosome	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

membrane coat [inference]

clathrin coat [inference]

clathrin coat of coated pit

plasma membrane protein complex [inference]

clathrin coat of coated pit

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body [inference]

neurofibrillary tangle

cell surface

membrane

plasma membrane

plasma membrane region [inference]

clathrin-coated pit

synaptic membrane [inference]

extrinsic component of membrane [inference]

extrinsic component of plasma membrane [inference]

extrinsic component of synaptic membrane [inference]

extrinsic component of presynaptic membrane [inference]

extrinsic component of presynaptic endocytic zone membrane

cell junction [inference]

synapse [inference]

excitatory synapse [inference]

parallel fiber to Purkinje cell synapse

Schaffer collateral - CA1 synapse

organelle [inference]

membrane-bounded organelle [inference]

vesicle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

early endosome

transport vesicle [inference]

exocytic vesicle [inference]

coated vesicle [inference]

clathrin-coated vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

postsynaptic specialization [inference]

postsynaptic density

cell body [inference]

neuronal cell body

Displaying entries **6 - 10** of 21 in total

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GO Term	Evidence Code	PMID
1-phosphatidylinositol binding	IBA
phosphatidylinositol-4,5-bisphosphate binding	ISO
phosphatidylinositol-4,5-bisphosphate binding	IBA
SH3 domain binding	ISO
clathrin binding	ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

SNARE binding

signaling receptor binding [inference]

lipoprotein particle receptor binding [inference]

low-density lipoprotein particle receptor binding

cytoskeletal protein binding [inference]

tau protein binding

enzyme binding [inference]

GTPase binding [inference]

small GTPase binding

protein domain specific binding [inference]

SH3 domain binding

clathrin binding

clathrin heavy chain binding

identical protein binding

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding [inference]

1-phosphatidylinositol binding

phosphatidylinositol phosphate binding [inference]

phosphatidylinositol bisphosphate binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

ion binding [inference]

anion binding [inference]

phosphatidylinositol-4,5-bisphosphate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

phosphatidylinositol binding clathrin assembly protein a

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 8** entries
Gene Ontology
1-phosphatidylinositol binding
SNARE binding
clathrin binding
clathrin coat assembly
clathrin heavy chain binding
clathrin-dependent endocytosis
phosphatidylinositol-4,5-bisphosphate binding
phospholipid binding

Displaying **all 5** entries
InterPro
ANTH domain superfamily
AP180 N-terminal homology (ANTH) domain
Clathrin coat assembly protein AP180-like
ENTH domain
ENTH/VHS

Ortholog

Displaying entries **1 - 10** of 73 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8301	ZFIN:ZDB-GENE-030131-6795	HUMAN08619
Saccharomyces cerevisiae S288C	9892	SGD:S000003473
Saccharomyces cerevisiae S288C	20616	SGD:S000001204
Saccharomyces cerevisiae S288C	65178	SGD:S000001204
Rattus norvegicus	89816	ZFIN:ZDB-GENE-040426-761	RATNO18380
Danio rerio	233489	ZFIN:ZDB-GENE-030131-6795
Danio rerio	393901		DANRE00450
Pan troglodytes	451725		PANTR03991
Macaca mulatta	706003		MACMU08952
Monodelphis domestica	100016924		MONDO23474

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements