GlyCosmos Portal

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GO Term	Evidence Code	PMID
collagen-containing extracellular matrix	IDA	16157329 1632457
collagen-containing extracellular matrix	HDA	20551380 23658023 23979707 25037231 27559042 28327460 28344315 28675934
extracellular exosome	IDA	21276792
extracellular exosome	HDA	19056867 23533145
blood microparticle	HDA	22516433

GO Hierarchy

cellular component

protein-containing complex [inference]

fibrinogen complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

external encapsulating structure [inference]

extracellular matrix

collagen-containing extracellular matrix

basement membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

vesicle lumen [inference]

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

cytoplasmic vesicle lumen [inference]

secretory granule lumen [inference]

platelet alpha granule lumen

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum-Golgi intermediate compartment

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

blood microparticle

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
protease binding	IPI	22952693
signaling receptor binding	IDA	34089617
integrin binding	IDA	19738201 33962943
integrin binding	IMP	24658351
integrin binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

binding [inference]

protein binding

signaling receptor binding

enzyme binding [inference]

protease binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

proteoglycan binding

sulfur compound binding [inference]

heparin binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme activator activity [inference]

peptidase activator activity

peptidase regulator activity [inference]

peptidase activator activity

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity

molecular function activator activity [inference]

enzyme activator activity [inference]

peptidase activator activity

signaling receptor activator activity [inference]

receptor ligand activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

fibronectin

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
acute-phase response
cell-matrix adhesion
extracellular matrix structural constituent
heparin binding
integrin binding
nervous system development
proteoglycan binding

Displaying **all 7** entries
InterPro
Fibronectin type II domain superfamily
Fibronectin type II domain
Fibronectin type III superfamily
Fibronectin type III
Fibronectin, type I
Immunoglobulin-like fold
Kringle-like fold

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080652	calcium oxalate nephrolithiasis	Alliance of Genome Resources
DOID:0112297	spondylometaphyseal dysplasia corner fracture type	Alliance of Genome Resources
DOID:2920	membranoproliferative glomerulonephritis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	2335	Xenbase:XB-GENE-484447
Mus musculus	14268	Xenbase:XB-GENE-484447	MOUSE30322
Rattus norvegicus	25661		RATNO43822
Bos taurus	280794		BOVIN24710
Sus scrofa	397620		PIGXX09945
Canis lupus familiaris	403845		CANLF14199
Pan troglodytes	459926		PANTR29720
Macaca mulatta	613269		MACMU05760
Danio rerio	100005469		DANRE44295
Monodelphis domestica	100014118		MONDO32217

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements