nicastrin
| UniProt | Protein Name |
|---|---|
| A0A8V8TPQ8 |
|
| B4DR82 |
|
| Q92542 |
|
| A0A8V8TPR8 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| myeloid cell homeostasis | ||
| proteolysis | ||
| membrane protein ectodomain proteolysis | ||
| dopamine receptor signaling pathway | ||
| glutamate receptor signaling pathway |
| GO Term | Evidence Code | PMID |
|---|---|---|
| Golgi membrane | ||
| lysosomal membrane | ||
| early endosome | ||
| endoplasmic reticulum | ||
| endoplasmic reticulum membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| protein-macromolecule adaptor activity | ||
| protein-macromolecule adaptor activity | ||
| aspartic endopeptidase activity, intramembrane cleaving | ||
| ATPase binding |
| Gene Ontology |
|---|
| Notch receptor processing |
| InterPro |
|---|
| Nicastrin, small lobe |
| Nicastrin |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10652 | Alzheimer's disease | |
| DOID:2280 | hidradenitis suppurativa | |
| DOID:5419 | schizophrenia |
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Last updated: December 8, 2025