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sorbin and SH3 domain containing 2

Summary

Gene Symbol

Sorbs2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

234214

PubChem

234214

Alliance of Genome Resources

MGI:1924574

Annotation

Keyword

Alternative splicing
Cell junction
Cell membrane
Cell projection
Cytoskeleton
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
SH3 domain
Ubl conjugation

Proteins

Displaying **all 6** entries
UniProt	Protein Name
D3Z080
B7ZWM6
Q3UTJ2	Arg-binding protein 2 Arg/Abl-interacting protein 2
B2RXQ9
A0A0S3CWK3
B9EKP8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Notch signaling pathway	IDA	23117660
Notch signaling pathway	IBA
cell growth involved in cardiac muscle cell development	ISO
acetylcholine receptor signaling pathway	IGI	26527617
regulation of skeletal muscle acetylcholine-gated channel clustering	IGI	26527617

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

cell growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

growth [inference]

cell growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

developmental growth [inference]

developmental cell growth [inference]

cell growth involved in cardiac muscle cell development

biological regulation [inference]

regulation of biological process [inference]

regulation of localization [inference]

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

regulation of skeletal muscle acetylcholine-gated channel clustering

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

postsynaptic signal transduction [inference]

acetylcholine receptor signaling pathway

regulation of cellular localization [inference]

regulation of protein localization [inference]

regulation of protein localization to membrane [inference]

regulation of receptor clustering [inference]

regulation of skeletal muscle acetylcholine-gated channel clustering

Displaying entries **1 - 5** of 14 in total

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GO Term	Evidence Code	PMID
cytoskeleton	IEA
plasma membrane	IDA	21689717
plasma membrane	IBA
focal adhesion	IEA
apical plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

Z disc

cell junction [inference]

synapse

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

neuron projection [inference]

dendrite

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

cell body [inference]

neuronal cell body

perinuclear region of cytoplasm

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	26527617
protein domain specific binding	IPI	21689717
identical protein binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sh3 domain-containing

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
SH3 domain
SH3-like domain superfamily
SoHo domain

Ortholog

Displaying entries **1 - 10** of 28 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8470	Xenbase:XB-GENE-478190	HUMAN78365
Caenorhabditis elegans	10174	WB:WBGene00012891
Caenorhabditis elegans	10580	WB:WBGene00012891
Caenorhabditis elegans	20410	WB:WBGene00012891
Caenorhabditis elegans	59009	WB:WBGene00012891
Rattus norvegicus	114901		RATNO10844
Xenopus tropicalis	234214	Xenbase:XB-GENE-478190
Pan troglodytes	461640		PANTR34923
Macaca mulatta	696139		MACMU36521
Pongo abelii	100172173		PONAB27292