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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
folate receptor alpha
Summary
- Gene Symbol
-
- FOLR1
- Aliases
-
- FRĪ±
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cell membrane
- Cytoplasmic vesicle
- Direct protein sequencing
- Disulfide bond
- Endosome
- Folate-binding
- GPI-anchor
- Neurodegeneration
- Receptor
- Reference proteome
- Secreted
- Signal
- Transport
- Proteins
| UniProt | Protein Name |
|---|---|
| P15328 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of canonical Wnt signaling pathway | ||
| neural crest cell migration involved in heart formation | ||
| sperm-egg recognition | ||
| heart looping | ||
| fusion of sperm to egg plasma membrane involved in single fertilization |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| brush border membrane | ||
| membrane |
|
|
| apical plasma membrane | ||
| extracellular exosome | ||
| Golgi membrane |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| folic acid receptor activity | ||
| folic acid binding | ||
| signaling receptor activity | ||
| protein binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3498 | pancreatic ductal adenocarcinoma | |
| DOID:3565 | meningioma | |
| DOID:3571 | liver cancer | |
| DOID:363 | uterine cancer | |
| DOID:3744 | cervical squamous cell carcinoma | |
| DOID:3772 | intraventricular meningioma | |
| DOID:3829 | pituitary adenoma | |
| DOID:3861 | medullomyoblastoma | |
| DOID:3864 | adult medulloblastoma | |
| DOID:3868 | melanotic medulloblastoma |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0001249 | Intellectual disability |
| HP:0001250 | Seizure |
| HP:0002180 | Neurodegeneration |
| HP:0002376 | Developmental regression |
| Disease ID | Disease Name |
|---|---|
| OMIM:613068 |
|
PubChem Disease
- GHR Health Conditions
- MedGen Diseases
- OMIM Phenotypes
- KEGG Diseases
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 102026741 | CHILA03837 | ||
| 105720385 | AOTNA04430 | ||
| 110195206 | PHACI03472 | ||
| 110195207 | PHACI03468 | ||
| 101054127 | SAIBB06061 | ||
| 101966601 | ICTTR04851 | ||
| 101606915 | JACJA01920 | ||
| 118299701 | SCOMX22616 | ||
| 102417105 | MYOLU08607 | ||
| 117030240 | RHIFE29567 |
